Refractory Nodular Lymphocyte Predominant Hodgkin Lymphoma Transformed to T-cell/Histiocyte-rich B-cell Lymphoma in an Adolescent Salvage Therapy With Allogeneic Bone Marrow Transplantation

被引：3
|
作者：
Couronne, Lucile [1 ]
Schneider, Pascale [1 ]
Picquenot, Jean Michel [2 ,3 ]
Laberge, Sophie [2 ,3 ]
Bastard, Christian [2 ,3 ]
Vannier, Jean Pierre [1 ]
机构：
[1] Hop Charles Nicolle, F-76000 Rouen, France
[2] Ctr Henri Becquerel, Dept Pathol, F-76038 Rouen, France
[3] Ctr Henri Becquerel, Dept Cytogenet, F-76038 Rouen, France
来源：
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY | 2008年 / 30卷 / 12期
关键词：
Poppema lymphoma; T-cell/histiocyte-rich B-cell lymphoma; allogeneic bone marrow transplantation; autologous bone marrow transplantation;
D O I：
10.1097/MPH.0b013e31818a9564
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
According to biologic features, there is it substantial "gray zone". between nodular lymphocyte predominant Hodgkin lymphomas (NLPHLs) (Poppema lymphomas) and T-cell/histiocyte-rich B-cell lymphomas (T/HRBCLs). Transformation from,in NLPHL to a T/HRBCL can Occur and is associated with a worsening of the prognosis. Here is described a case of a 16-year-old boy who presented with an NLPHL with features of T/HRBCL. Clinical evolution was complicated by 2 relapses leading to autologous and then to allogeneic bone marrow transplantation.
引用
收藏
页码：959 / 962
页数：4
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