Effect of 99mTc elution in vivo from red cells on red cell volumes measured using autologous 99mTc-labeled red cells: comparison with 51Cr method

被引：2

作者：

Galletl, Matthieu ^{[1
]}

Drouet, Clement ^{[2
]}

Girodon, Francois ^{[3
,4
]}

Nicolas, Alexandra ^{[1
]}

Riedinger, Jean-Marc ^{[1
,5
]}

机构：

[1] Ctr Georges Francois Leclerc, Unite Radiopharm, Dijon, France

[2] Ctr Georges Francois Leclerc, Serv Med Nucl, Dijon, France

[3] CHU Dijon, Serv Hematol Biol, Pole Biol, Dijon, France

[4] Univ Bourgogne, INSERM, U1231, Dijon, France

[5] Ctr Georges Francois Leclerc, Dept Biol & Pathol Tumeurs, Unite Biol Clin, Dijon, France

来源：

ANNALES DE BIOLOGIE CLINIQUE | 2020年 / 78卷 / 03期

关键词：

polycythemia vera; erythrosis; red cell volume; HEALTH; MASS;

D O I：

10.1684/abc.2020.1547

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

The purpose of this work was to compare the measured red-cell volume (RCV) using sodium pertechnetate [RCV-Tc-99m] compared to the reference technique using sodium radiochromate [RCV-Cr-51] and to assess the influence of technetium-99 elution on the RCV-Tc-99m value. Ten patients had simultaneous measurements of RCV-Tc-99m and RCV-Cr-51. Elution of Tc-99m from red blood cells was 2.9% and led to an average overestimation of RCV-Tc-99m of 3.7%. The introduction of individual tracer elution rates in the RCV-Tc-99m calculation corrects this overestimation.

引用

页码：319 / 322

页数：4

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