Effect of 99mTc elution in vivo from red cells on red cell volumes measured using autologous 99mTc-labeled red cells: comparison with 51Cr method

被引：2
|
作者：
Galletl, Matthieu [1 ]
Drouet, Clement [2 ]
Girodon, Francois [3 ,4 ]
Nicolas, Alexandra [1 ]
Riedinger, Jean-Marc [1 ,5 ]
机构：
[1] Ctr Georges Francois Leclerc, Unite Radiopharm, Dijon, France
[2] Ctr Georges Francois Leclerc, Serv Med Nucl, Dijon, France
[3] CHU Dijon, Serv Hematol Biol, Pole Biol, Dijon, France
[4] Univ Bourgogne, INSERM, U1231, Dijon, France
[5] Ctr Georges Francois Leclerc, Dept Biol & Pathol Tumeurs, Unite Biol Clin, Dijon, France
来源：
ANNALES DE BIOLOGIE CLINIQUE | 2020年 / 78卷 / 03期
关键词：
polycythemia vera; erythrosis; red cell volume; HEALTH; MASS;
D O I：
10.1684/abc.2020.1547
中图分类号：
R446 [实验室诊断]; R-33 [实验医学、医学实验];
学科分类号：
1001 ;
摘要：
The purpose of this work was to compare the measured red-cell volume (RCV) using sodium pertechnetate [RCV-Tc-99m] compared to the reference technique using sodium radiochromate [RCV-Cr-51] and to assess the influence of technetium-99 elution on the RCV-Tc-99m value. Ten patients had simultaneous measurements of RCV-Tc-99m and RCV-Cr-51. Elution of Tc-99m from red blood cells was 2.9% and led to an average overestimation of RCV-Tc-99m of 3.7%. The introduction of individual tracer elution rates in the RCV-Tc-99m calculation corrects this overestimation.
引用
收藏
页码：319 / 322
页数：4
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