A FRET-based rhodamine-benzimidazole conjugate as a Cu2+-selective colorimetric and ratiometric fluorescence probe that functions as a cytoplasm marker

被引:42
|
作者
Goswami, Shyamaprosad [1 ]
Maity, Sibaprasad [1 ,2 ]
Maity, Annada C. [1 ]
Maity, Anup Kumar [3 ]
Das, Avijit Kumar [1 ]
Saha, Partha [3 ]
机构
[1] Bengal Engn & Sci Univ, Dept Chem, Howrah 711103, W Bengal, India
[2] Haldia Inst Technol, Dept Appl Sci, Haldia 721657, W Bengal, India
[3] Saha Inst Nucl Phys, Crystallog & Mol Biol Div, Kolkata 700064, W Bengal, India
来源
RSC ADVANCES | 2014年 / 4卷 / 12期
关键词
OFF-ON; SENSOR; CU2+; CHEMOSENSOR; FLUORIDE; RING; FLUOROIONOPHORE; SPIROLACTAM; SELECTIVITY; CHEMISTRY;
D O I
10.1039/c3ra46280c
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
On the basis of fluorescence resonance energy transfer (FRET) from benzimidazole to a rhodamine moiety, a rhodamine-benzimidazole conjugate (RBC) ratiometric fluorescent probe has been designed and synthesized. The RBC selectively binds to Cu2+, showing visually observable changes in absorption and emission behavior, and demonstrates an effective intracellular Cu2+ imaging ability, allowing it to function as a cytoplasm marker.
引用
收藏
页码:6300 / 6305
页数:6
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