An approach to oxazolidin-2-ones from the Baylis-Hillman adducts. Formal synthesis of a chloramphenicol derivative

被引：46
|
作者：
Coelho, F [1 ]
Rossi, RC [1 ]
机构：
[1] Univ Estadual Campinas, DQO, IQ, BR-13083970 Campinas, SP, Brazil
来源：
TETRAHEDRON LETTERS | 2002年 / 43卷 / 15期
关键词：
oxazolidin-2-one; Baylis-Hillman reaction; chloramphenicol derivative;
D O I：
10.1016/S0040-4039(02)00351-9
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
In this communication we describe a straightforward and diastereoselective approach to prepare functionalised oxazolidin-2-ones from Baylis-Hillinan adducts. A stereoselective synthesis of a highly Substituted vicinal aminoalcohol and a formal synthesis of a chloramphenicol derivative are also described. (C) 2002 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码：2797 / 2800
页数：4
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