Novel preclinical models and biomarkers for prostate cancer

被引：0
|
作者：
Korzeniewski, N. [1 ]
Tapia-Laliena, M. [1 ]
Tolstov, Y. [1 ]
Pahernik, S. [2 ]
Hadaschik, B. [2 ]
Hohenfellner, M. [2 ]
Duensing, S. [1 ,2 ]
机构：
[1] Univ Klinikum Heidelberg, Sekt Mol Uroonkol, Urol Univ Klin, D-69120 Heidelberg, Germany
[2] Univ Klinikum Heidelberg, Urol Univ Klin, D-69120 Heidelberg, Germany
来源：
UROLOGE | 2013年 / 52卷 / 09期
关键词：
Therapy; oncological; Genetically engineered mouse model; Xenograft model; Androgen ablation; Metastasization; osseous; REARRANGEMENT; MECHANISMS; FUSION;
D O I：
10.1007/s00120-013-3310-6
中图分类号：
R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];
学科分类号：
1002 ; 100201 ;
摘要：
The ultimate goal of a personalized approach to prostate cancer patient management relies on two prerequisites: the development of preclinical but clinically relevant model systems and robust prognostic and predictive biomarkers. The past several years have shown significant progress towards these two prerequisites which will be highlighted in this review using some notable examples.
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页码：1256 / 1260
页数：5
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