Bacterial Synthesis of Diverse Indole Terpene Alkaloids by an Unparalleled Cyclization Sequence

被引：108
|
作者：
Xu, Zhongli [1 ]
Baunach, Martin [1 ]
Ding, Ling [1 ]
Hertweck, Christian [1 ,2 ]
机构：
[1] HKI, Leibniz Inst Nat Prod Res & Infect Biol, Dept Biomol Chem, D-07745 Jena, Germany
[2] Univ Jena, Chair Nat Prod Chem, Jena, Germany
来源：
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2012年 / 51卷 / 41期
关键词：
alkaloids; indole oxygenase; indolosesquiterpenes; terpene cyclase; xiamycin; GENE-CLUSTER; BIOSYNTHESIS; STREPTOMYCES; ISOPRENOIDS; METABOLISM; DITERPENE; OXIDATION; INSIGHTS; REVEALS; PATHWAY;
D O I：
10.1002/anie.201204087
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
引用
收藏
页码：10293 / 10297
页数：5
相关论文
共 50 条
  • [31] Efficient and Diverse Synthesis of Indole Derivatives
    Liu, Haixia
    Doemling, Alexander
    JOURNAL OF ORGANIC CHEMISTRY, 2009, 74 (17): : 6895 - 6898
  • [32] STUDIES ON FISCHER INDOLE CYCLIZATION - SYNTHESIS OF NITROINDOLES
    SALEHA, S
    SIDDIQI, AA
    KHAN, NH
    INDIAN JOURNAL OF CHEMISTRY SECTION B-ORGANIC CHEMISTRY INCLUDING MEDICINAL CHEMISTRY, 1979, 17 (06): : 636 - 636
  • [33] Organocascade catalysis: Application to the synthesis of indole alkaloids
    Mastracchio, Anthony
    MacMillan, David W. C.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
  • [34] Fluorous and traceless synthesis of substituted indole alkaloids
    Lin, Mei-Jung
    Zhang, Wei
    Sun, Chung-Ming
    JOURNAL OF COMBINATORIAL CHEMISTRY, 2007, 9 (06): : 951 - 958
  • [35] Studies on the synthesis of antitumor indole alkaloids.
    Magnus, PD
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 1999, 218 : U16 - U16
  • [36] A general method for the synthesis of bridged indole alkaloids
    Bosch, J
    Bennasar, ML
    Amat, M
    PURE AND APPLIED CHEMISTRY, 1996, 68 (03) : 557 - 560
  • [37] Oxidative coupling strategies for the synthesis of indole alkaloids
    Nagaraju, Karre
    Ma, Dawei
    CHEMICAL SOCIETY REVIEWS, 2018, 47 (21) : 8018 - 8029
  • [38] FORMAL SYNTHESIS OF THE INDOLE ALKALOIDS NGOUNIENSINE AND EPINGOUNIENSINE
    BENNASAR, ML
    ZULAICA, E
    VILA, R
    BOSCH, J
    HETEROCYCLES, 1989, 29 (02) : 381 - 390
  • [39] Studies on the synthesis of the indole alkaloids pauciflorine A and B
    Magnus, P
    Gazzard, L
    Hobson, L
    Payne, AH
    Lynch, V
    TETRAHEDRON LETTERS, 1999, 40 (28) : 5135 - 5138
  • [40] Recent progress in the total synthesis of indole alkaloids
    Edwankar, Chitra R.
    Edwankar, Rahul V.
    Namjoshi, Ojas A.
    Rallapalli, Sundari K.
    Yang, Jie
    Cook, James M.
    CURRENT OPINION IN DRUG DISCOVERY & DEVELOPMENT, 2009, 12 (06) : 752 - 771
12345