EXPRESSION OF SYNAPTIC VESICLE PROTEIN 2A (SV2A), THE BINDING SITE FOR LEVETIRACETAM, IN EPILEPSY-ASSOCIATED BRAIN TUMORS AND IN THE PERILESIONAL EPILEPTIC CORTEX

被引：0
|
作者：
Toering, S. T. [1 ]
Boer, K. [2 ]
Heimans, J. J. [1 ]
Aronica, E. [2 ]
Reijneveld, J. C. [1 ,2 ]
机构：
[1] Vrije Univ Amsterdam Med Ctr, Amsterdam, Netherlands
[2] Univ Amsterdam, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands
来源：
NEURO-ONCOLOGY | 2008年 / 10卷 / 06期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：1147 / 1147
页数：1
相关论文
共 50 条
  • [31] Development and In Vivo Preclinical Imaging of Fluorine-18-Labeled Synaptic Vesicle Protein 2A (SV2A) PET Tracers
    Cristian C. Constantinescu
    Cedric Tresse
    MingQiang Zheng
    Alexandra Gouasmat
    Vincent M Carroll
    Laetitia Mistico
    David Alagille
    Christine M. Sandiego
    Caroline Papin
    Kenneth Marek
    John P. Seibyl
    Gilles D. Tamagnan
    Olivier Barret
    Molecular Imaging and Biology, 2019, 21 : 509 - 518
  • [32] An Epilepsy-Associated SV2A Mutation Disrupts Synaptotagmin-1 Expression and Activity-Dependent Trafficking
    Harper, Callista B.
    Small, Christopher
    Davenport, Elizabeth C.
    Low, Darryl W.
    Smillie, Karen J.
    Martinez-Marmol, Ramon
    Meunier, Frederic A.
    Cousin, Michael A.
    JOURNAL OF NEUROSCIENCE, 2020, 40 (23): : 4586 - 4595
  • [33] Development and In Vivo Preclinical Imaging of Fluorine-18-Labeled Synaptic Vesicle Protein 2A (SV2A) PET Tracers
    Constantinescu, Cristian C.
    Tresse, Cedric
    Zheng, MingQiang
    Gouasmat, Alexandra
    Carroll, Vincent M.
    Mistico, Laetitia
    Alagille, David
    Sandiego, Christine M.
    Papin, Caroline
    Marek, Kenneth
    Seibyl, John P.
    Tamagnan, Gilles D.
    Barret, Olivier
    MOLECULAR IMAGING AND BIOLOGY, 2019, 21 (03) : 509 - 518
  • [34] Preparation of 99mTc-levetiracetam intranasal microemulsion as the first radiotracer for SPECT imaging of the Synaptic Vesicle Protein SV2A
    Rashed, Hassan M.
    Shamma, Rehab N.
    El-Sabagh, Hanan A.
    EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2018, 121 : 29 - 33
  • [35] HIGH SV2A EXPRESSION IN TUMOR AND PERITUMORAL TISSUE IN GLIOMA PATIENTS WITH EPILEPSY IS ASSOCIATED WITH HIGH EFFICACY OF LEVETIRACETAM
    de Groot, M.
    Aronica, E.
    Vecht, C. J.
    Toering, S. T.
    Heimans, J. J.
    Reijneveld, J. C.
    NEURO-ONCOLOGY, 2010, 12 : 75 - 75
  • [36] Brivaracetam, a selective high-affinity synaptic vesicle protein 2A (SV2A) ligand with preclinical evidence of high brain permeability and fast onset of action
    Nicolas, Jean-Marie
    Hannestad, Jonas
    Holden, Daniel
    Kervyn, Sophie
    Nabulsi, Nabeel
    Tytgat, Dominique
    Huang, Yiyun
    Chanteux, Hugues
    Staelens, Ludovicus
    Matagne, Alain
    Mathy, Francois-Xavier
    Mercier, Joel
    Stockis, Armel
    Carson, Richard E.
    Klitgaard, Henrik
    EPILEPSIA, 2016, 57 (02) : 201 - 209
  • [37] NEGATIVE MODULATION OF THE SYNAPTIC VESICLE PROTEIN (SV2A): A NEW PHARMACOLOGICAL TARGET FOR COGNITIVE DEFICIT ASSOCIATED WITH SCHIZOPHRENIA
    Laruelle, Marc
    Detrait, Eric
    Lamberty, Yves
    Leclercq, Karine
    Jnoff, Eric
    Wood, Martin
    Gillard, Michel
    Jigorel, Emilie
    Klitgaard, Henrik
    Provins, Laurent
    SCHIZOPHRENIA RESEARCH, 2014, 153 : S66 - S66
  • [38] Negative Modulation of the Synaptic Vesicle Protein (SV2A): A New Pharmacological Target for Cognitive Deficit Associated with Schizophrenia
    Detrait, Eric R.
    Laruelle, Marc
    Lamberty, Yves
    Leclercq, Karine
    Jnoff, Eric
    Wood, Martyn
    Gillard, Michel
    Jigorel, Emilie
    Klitgaard, Henrik
    Provins, Laurent
    BIOLOGICAL PSYCHIATRY, 2014, 75 (09) : 133S - 133S
  • [39] Analysis of Differential Expression of Synaptic Vesicle Protein 2A in the Adult Rat Brain
    Mendoza-Torreblanca, Julieta G.
    Edna Garcia-Cruz, M.
    Sanchez-Cruz, Itzel
    Gomez-Gonzalez, Beatriz
    Juarez-Mendez, Sergio
    Gomez-Lira, Gisela
    NEUROSCIENCE, 2019, 419 : 108 - 120
  • [40] Monitoring synaptic loss in a rat model of stroke: a PET imaging study with [18F]SynVesT-2, radiotracer for the synaptic vesicle protein 2A (SV2A)
    Lyu, Xueying
    Toyonaga, Takuya
    Deng, Gang
    Huang, Yiyun
    Carson, Richard
    Zhou, Jiangbing
    Cai, Zhengxin
    JOURNAL OF NUCLEAR MEDICINE, 2020, 61
12345