Synthesis and antioxidant activity of biocompatible maltodextrin-stabilized aqueous sols of nanocrystalline ceria

被引：28
|
作者：
Shcherbakov, A. B. [1 ]
Zholobak, N. M. [1 ]
Ivanov, V. K. [2 ,3 ]
Ivanova, O. S. [2 ]
Marchevsky, A. V. [3 ]
Baranchikov, A. E. [2 ]
Spivak, N. Ya [1 ]
Tretyakov, Yu D. [2 ,3 ]
机构：
[1] Natl Acad Sci Ukraine, Zabolotny Inst Microbiol & Virol, Kiev, Ukraine
[2] Russian Acad Sci, Kurnakov Inst Gen & Inorgan Chem, Moscow 119991, Russia
[3] Moscow MV Lomonosov State Univ, Dept Mat Sci, Moscow 119992, Russia
来源：
RUSSIAN JOURNAL OF INORGANIC CHEMISTRY | 2012年 / 57卷 / 11期
基金：
俄罗斯基础研究基金会;
关键词：
OXIDATIVE STRESS;
D O I：
10.1134/S0036023612110137
中图分类号：
O61 [无机化学];
学科分类号：
070301 ; 081704 ;
摘要：
A novel method is proposed for preparing biocompatible aqueous CeO2 sols, which allows purposefully adjusting particle sizes and biochemical properties of nanocrystalline ceria (NC). The usefulness of this method for preparing aqueous sols of Ce1 - x Gd (x) O2 - x/2 solid solutions is demonstrated. Nanocrystalline ceria has been demonstrated to have a size-dependent activity in hydroxyl radical inactivation and in protecting mouse fibroblast cells (L929) from oxidative stress induced by hydrogen peroxide administration.
引用
收藏
页码：1411 / 1418
页数：8
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