Development of a sensitive fiber optic sensor monitoring NO based on vicinal diaminobenzoacridine fluorophore

被引：1

作者：

Ding, Liyun ^{[1
]}

Fan, Chao ^{[1
]}

Huang, Jun ^{[1
]}

Liang, Bing ^{[2
,3
]}

Yuan, Fang ^{[2
,3
]}

Gong, Daoren ^{[4
]}

机构：

[1] Wuhan Univ Technol, Natl Engn Lab Fiber Opt Sensing Technol, Wuhan 430070, Peoples R China

[2] Inst Neurosci, Minist Educ China, Key Lab Neurogenet & Channelopathies Guangdong Pr, Guangzhou 510260, Peoples R China

[3] GuangZhou Med Univ, Affiliated Hosp 2, Guangzhou 510260, Peoples R China

[4] Yangzhou Opto Elect Prod Testing Inst, State Key Lab Opto Elect Prod Inspect, Yangzhou 225009, Jiangsu, Peoples R China

来源：

22ND INTERNATIONAL CONFERENCE ON OPTICAL FIBER SENSORS, PTS 1-3 | 2012年 / 8421卷

基金：

中国国家自然科学基金;

关键词：

Fiber optic NO sensor; fluorescence; sensitive membrane; vicinal diaminobenzoacridine; NITRIC-OXIDE; CELLULAR APPLICATIONS;

D O I：

10.1117/12.966843

中图分类号：

TP7 [遥感技术];

学科分类号：

081102 ; 0816 ; 081602 ; 083002 ; 1404 ;

摘要：

A new fiber optic sensor has been developed for determination of NO using a fluorescent vicinal diaminobenzoacridine (VDABA) probe. The sensitive membrane was prepared from cellulose acetate (CA) embedded with VDABA, which caused a fluorescence recovery based on a photoelectron transfer (PET) mechanism. Modulation of optical phase shift of the sensor is observed with different NO concentrations. Under optimum conditions, a linear calibration (r(2)=0.9902) was obtained in the range of 1.0x10(-8) to 1.0x10(-5) mol/L NO concentration with a detection limit of 1.0x10(-9) mol/L (S/N=3). This sensor was successfully applied to the determination of NO in the rabbit serum.

引用

页数：4

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