Combined BRAF and MEK Inhibition with Dabrafenib and Trametinib in BRAF V600-mutant colorectal cancer

被引：0
|
作者：
Loir, E. [1 ]
Cochereau, D. [1 ]
机构：
[1] AERIO, Paris, France
来源：
ONCOLOGIE | 2016年 / 18卷 / 9-10期
关键词：
IMPROVED SURVIVAL; VEMURAFENIB; MELANOMA;
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
引用
收藏
页码：565 / 566
页数：2
相关论文
共 50 条
  • [41] Phase Ib study of dabrafenib, trametinib, irinotecan and cetuximab in BRAF V600Emutated metastatic colorectal cancer.
    Chen, Yungchang
    Li, Xiaoqian
    Man Yuxin
    Hu, Hai
    Wang, Liyang
    Zhang, Zhixuan
    Chen, Ping
    Liu, Yang
    Lu, Jin
    Lin, Tongyu
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 : 156 - 156
  • [42] Prolonged Complete Response With Combined Dabrafenib and Trametinib After BRAF Inhibitor Failure in BRAF-Mutant Glioblastoma
    Kushnirsky, Marina
    Feun, Lynn G.
    Gultekin, Sakir H.
    de la Fuente, Macarena I.
    [J]. JCO PRECISION ONCOLOGY, 2020, 4 : 44 - 50
  • [43] BRAF V600 mutant colorectal cancer (CRC) expansion cohort from the phase I/II clinical trial of BRAF inhibitor dabrafenib (GSK2118436) plus MEK inhibitor trametinib (GSK1120212)
    Corcoran, Ryan Bruce
    Falchook, Gerald Steven
    Infante, Jeffrey R.
    Hamid, Omid
    Messersmith, Wells A.
    Kwak, Eunice Lee
    Ryan, David P.
    Kurzrock, Razelle
    Brenner, Adrienne A.
    Luan, Jennifer
    Sun, Peng
    Allred, Alicia J.
    Little, Shonda M.
    Patel, Kiran
    Kopetz, Scott
    Venook, Alan Paul
    [J]. JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (15)
  • [44] Survival in BRAF V600-Mutant Advanced Melanoma Treated with Vemurafenib
    Sosman, Jeffrey A.
    Kim, Kevin B.
    Schuchter, Lynn
    Gonzalez, Rene
    Pavlick, Anna C.
    Weber, Jeffrey S.
    McArthur, Grant A.
    Hutson, Thomas E.
    Moschos, Stergios J.
    Flaherty, Keith T.
    Hersey, Peter
    Kefford, Richard
    Lawrence, Donald
    Puzanov, Igor
    Lewis, Karl D.
    Amaravadi, Ravi K.
    Chmielowski, Bartosz
    Lawrence, H. Jeffrey
    Shyr, Yu
    Ye, Fei
    Li, Jiang
    Nolop, Keith B.
    Lee, Richard J.
    Joe, Andrew K.
    Ribas, Antoni
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2012, 366 (08): : 707 - 714
  • [45] BAMM (BRAF Autophagy and MEK Inhibition in Melanoma): A Phase I/II Trial of Dabrafenib, Trametinib, and Hydroxychloroquine in Advanced BRAFV600-mutant Melanoma
    Mehnert, Janice M.
    Mitchell, Tara C.
    Huang, Alexander C.
    Aleman, Tomas S.
    Kim, Benjamin J.
    Schuchter, Lynn M.
    Linette, Gerald P.
    Karakousis, Giorgos C.
    Mitnick, Sheryl
    Giles, Lydia
    Carberry, Mary
    Frey, Noelle
    Kossenkov, Andrew
    Groisberg, Roman
    Hernandez-Aya, Leonel F.
    Ansstas, George
    Silk, Ann W.
    Chandra, Sunandana
    Sosman, Jeffrey A.
    Gimotty, Phyllis A.
    Mick, Rosemarie
    Amaravadi, Ravi K.
    [J]. CLINICAL CANCER RESEARCH, 2022, 28 (06) : 1098 - 1106
  • [46] Histological transformation to gliosarcoma with combined BRAF/MEK inhibition in BRAF V600E mutated glioblastoma
    Blessie Elizabeth Nelson
    Neha K. Reddy
    Jason T. Huse
    Behrang Amini
    Mirella Nardo
    Mohamed Gouda
    Shiao-Pei Weathers
    Vivek Subbiah
    [J]. npj Precision Oncology, 7
  • [47] Histological transformation to gliosarcoma with combined BRAF/MEK inhibition in BRAF V600E mutated glioblastoma
    Nelson, Blessie Elizabeth
    Reddy, Neha K.
    Huse, Jason T.
    Amini, Behrang
    Nardo, Mirella
    Gouda, Mohamed
    Weathers, Shiao-Pei
    Subbiah, Vivek
    [J]. NPJ PRECISION ONCOLOGY, 2023, 7 (01)
  • [48] COMBI-r: A Prospective, Non-Interventional Study of Dabrafenib Plus Trametinib in Unselected Patients with Unresectable or Metastatic BRAF V600-Mutant Melanoma
    Berking, Carola
    Livingstone, Elisabeth
    Debus, Dirk
    Loquai, Carmen
    Weichenthal, Michael
    Leiter, Ulrike
    Kiecker, Felix
    Mohr, Peter
    Eigentler, Thomas K.
    Remy, Janina
    Schober, Katharina
    Heppt, Markus V.
    von Wasielewski, Imke
    Schadendorf, Dirk
    Gutzmer, Ralf
    [J]. CANCERS, 2023, 15 (18)
  • [49] Inhibition of BRAF and MEK in BRAF-mutant melanoma
    Smalley, Keiran S. M.
    Sondak, Vernon K.
    [J]. LANCET, 2015, 386 (9992): : 410 - 412
  • [50] Dabrafenib plus Trametinib: a Review in Advanced Melanoma with a BRAF V600 Mutation
    Dhillon, Sohita
    [J]. TARGETED ONCOLOGY, 2016, 11 (03) : 417 - 428
12345