Acute kidney injury as a complication of vasculitic polyneuropathy mimicking Guillain-Barre syndrome with positive anti-GM1 antibodies

被引:0
|
作者
Ahmed, A. K. [1 ]
Mowafi, W. [2 ]
Ellam, T. [1 ]
Khan, A. [2 ]
Angel, C. [3 ]
Wilkie, M.
McKane, W. [1 ]
El Nahas, A. M. [1 ]
机构
[1] No Gen Hosp, Sheffield Kidney Inst, Sheffield S5 7AU, S Yorkshire, England
[2] Royal Hallamshire Hosp, Dept Neurol, Sheffield S10 2JF, S Yorkshire, England
[3] No Gen Hosp, Dept Histopathol, Sheffield Teaching Hosp NHS Fdn Trust, Sheffield S5 7AU, S Yorkshire, England
关键词
D O I
10.1002/dat.20228
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
A 69-year-old male patient presented with acute ascending symmetric areflexic quadriplegia following an upper respiratory tract infection. The clinical presentation was initially typical of Guillain-Barre syndrome and was treated with intravenous immunoglobulin; however, he later developed acute kidney injury requiring hemodialysis. A renal biopsy showed medium-size arteritis compatible with polyarteritis nodosa (PAN). Subsequent immunological testing revealed positive anti-GM1 antibodies not previously reported in association with PAN. The patient was treated with methylprednisolone and cyclophosphamide as well as plasmapheresis. After 40 days, the patient made good renal functional recovery and was discharged for neurorehabilitation.
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页码:209 / +
页数:4
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