Boric acid catalyzed Ugi three-component reaction in aqueous media

被引：24
|
作者：
Kumar, Atul [1 ]
Saxena, Deepti [1 ]
Gupta, Maneesh Kumar [1 ]
机构：
[1] CSIR, Cent Drug Res Inst, Med & Proc Chem Div, Lucknow, Uttar Pradesh, India
来源：
RSC ADVANCES | 2013年 / 3卷 / 14期
关键词：
CORTICOTROPIN-RELEASING HORMONE; MICHAEL REACTIONS; ORGANIC-SYNTHESIS; GREEN CHEMISTRY; WATER; DERIVATIVES; RECEPTOR;
D O I：
10.1039/c3ra23087b
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
B(OH)(3) catalyzed Ugi three-component reaction for the synthesis of 2-arylamino-2-phenylacetamide has been developed using aldehydes, amines, and isocyanides in water. The synthesized 2-arylamino-2-phenylacetamides were efficiently converted into alpha-amino acid via acidic hydrolysis.
引用
收藏
页码：4610 / 4612
页数：3
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