simulation model;
sun protection;
sun protection factor;
sunburn;
sunscreens;
SUN PROTECTION FACTOR;
FLUORESCENCE SPECTROSCOPY;
UV EXPOSURE;
SKIN;
ULTRAVIOLET;
ATTITUDES;
MELANOMA;
RISK;
D O I:
10.1111/phpp.12033
中图分类号:
R75 [皮肤病学与性病学];
学科分类号:
100206 ;
摘要:
Background/Objective Sunburn is a common feature in sunscreen users. The purpose of this paper is to estimate the expected frequency and magnitude of sunburn resulting from typical use of sunscreens labelled SPF15 and SPF30 by people spending long periods outdoors in strong summer sunshine. Methods By combining the probability distribution of the measured sun protection factor (SPF) in vivo with those for the average application thickness and the uniformity of application over the skin surface, a simulation model was developed to estimate the variation in delivered protection over the exposed skin surface from consumer use of sunscreens. Results While either sunscreen, if delivering the nominal SPF over the entire exposed skin, would be sufficient to prevent any erythema, the simulation indicates that the combination of the average quantity applied with the variability in thickness over the skin surface will lead to erythema, especially in SPF15 sunscreen users. Conclusion People who intend spending long periods outside in strong sunshine would be better advised to use SPF30 labelled sunscreens than SPF15 sunscreens, and to apply the product carefully over exposed skin if they wish to minimize their risk of sunburn and, by implication, skin cancer.
机构:
Mashhad Univ Med Sci, Pharmaceut Res Ctr, Mashhad, Iran
Mashhad Univ Med Sci, Sch Pharm, Mashhad, IranMashhad Univ Med Sci, Pharmaceut Res Ctr, Mashhad, Iran
Golmohammadzadeh, Shiva
Jaafari, Mahmoud Reza
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机构:
Mashhad Univ Med Sci, Pharmaceut Res Ctr, Mashhad, Iran
Mashhad Univ Med Sci, Sch Pharm, Biotechnol Res Ctr, Mashhad, IranMashhad Univ Med Sci, Pharmaceut Res Ctr, Mashhad, Iran
Jaafari, Mahmoud Reza
Khalili, Noman
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机构:
Mashhad Univ Med Sci, Sch Pharm, Mashhad, IranMashhad Univ Med Sci, Pharmaceut Res Ctr, Mashhad, Iran
机构:
Air Force Gen Hosp, Dept Dermatol, Beijing, Peoples R ChinaAir Force Gen Hosp, Dept Dermatol, Beijing, Peoples R China
Liu, Wei
Wang, Xuemin
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机构:
Shanghai Skin Dis & STD Hosp, Dept Dermatol, Shanghai, Peoples R ChinaAir Force Gen Hosp, Dept Dermatol, Beijing, Peoples R China
Wang, Xuemin
Lai, Wei
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机构:
Sun Yat Sen Univ, Dept Dermatol, Affiliated Hosp 3, Guangzhou 510275, Guangdong, Peoples R ChinaAir Force Gen Hosp, Dept Dermatol, Beijing, Peoples R China
Lai, Wei
Yan, Tian
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Air Force Gen Hosp, Dept Dermatol, Beijing, Peoples R ChinaAir Force Gen Hosp, Dept Dermatol, Beijing, Peoples R China
Yan, Tian
Wu, Yanyu
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机构:
Shanghai Skin Dis & STD Hosp, Dept Dermatol, Shanghai, Peoples R ChinaAir Force Gen Hosp, Dept Dermatol, Beijing, Peoples R China
Wu, Yanyu
Wan, Miaojian
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机构:
Sun Yat Sen Univ, Dept Dermatol, Affiliated Hosp 3, Guangzhou 510275, Guangdong, Peoples R ChinaAir Force Gen Hosp, Dept Dermatol, Beijing, Peoples R China
Wan, Miaojian
Yi, Jinling
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机构:
Sun Yat Sen Univ, Dept Dermatol, Affiliated Hosp 3, Guangzhou 510275, Guangdong, Peoples R ChinaAir Force Gen Hosp, Dept Dermatol, Beijing, Peoples R China
Yi, Jinling
Matsui, Mary S.
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机构:
Estee Lauder Co, Melville, NY USAAir Force Gen Hosp, Dept Dermatol, Beijing, Peoples R China