HIV-1 Vpu: Putting a channel to the TASK

被引：7
|
作者：
Strebel, K [1 ]
机构：
[1] NIAID, Viral Biochem Sect, Mol Microbiol Lab, NIH, Bethesda, MD 20892 USA
来源：
MOLECULAR CELL | 2004年 / 14卷 / 02期
关键词：
D O I：
10.1016/S1097-2765(04)00205-9
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Vpu is an HIV-encoded protein that enhances virus release. Previously, this activity was correlated with an intrinsic ion channel activity of Vpu. In this issue of Molecular Cell, Hsu et al. (2004) propose an alternative mechanism: they suggest that Vpu functions by inhibiting another ion channel, TASK-1.
引用
收藏
页码：150 / 152
页数：3
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