Density and affinity of the dopamine D2 receptors in aged symptomatic and asymptomatic MPTP-treated monkeys:: PET studies with [11C]raclopride

被引:30
|
作者
Doudet, DJ
Jivan, S
Ruth, TJ
Holden, JE
机构
[1] Univ British Columbia, Dept Med, Div Neurol, Vancouver, BC V6T 2B5, Canada
[2] Univ British Columbia, TRIUMF, Vancouver, BC V6T 2B5, Canada
[3] Univ Wisconsin, Dept Med Phys, Madison, WI 53706 USA
关键词
D O I
10.1002/syn.10070
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
[No abstract available]
引用
收藏
页码:198 / 202
页数:5
相关论文
共 50 条
  • [41] In vivo vulnerability to endogenous dopamine:: Comparison of the dopamine-2 (D2) agonist tracer [11C]-n-propylnorapomorphine ([11C]NPA) with the D2 antagonist tracer [11C]raclopride.
    Narendran, R
    Talbot, PS
    Kegeles, LS
    Martinez, D
    Huang, Y
    Ngo, K
    Hackett, E
    Castrillon, J
    Abi-Dargham, A
    Laruelle, M
    Hwang, DR
    JOURNAL OF NUCLEAR MEDICINE, 2003, 44 (05) : 71P - 71P
  • [42] Precursor synthesis and radiolabelling of the dopamine D2 receptor ligand [11C]raclopride from [11C]methyl triflate
    Langer, O
    Någren, K
    Dolle, F
    Lundkvist, C
    Sandell, J
    Swahn, CG
    Vaufrey, F
    Crouzel, C
    Maziere, B
    Halldin, C
    JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS, 1999, 42 (12): : 1183 - 1193
  • [43] Can changes in extrastriatal binding to D2/3receptors be detected using PET/[11C]raclopride?
    Pretorius, L
    Asselin, MC
    NEUROIMAGE, 2004, 22 : T89 - T90
  • [44] In vivo quantification of striatal dopamine D2 receptor expression and [11C]raclopride affinity using a single injection protocol
    Fischer, Kristina
    Wimberley, Catriona
    Magg, Janine
    Huu Phuc Nguyen
    Gregoire, Marie-Claude
    Pichler, Bernd
    JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM, 2012, 32 : S68 - S69
  • [45] No "ceiling effect" observed with the exogenous dopamine agonist apomorphine -: A PET study with the dopamine D2 receptor agonist radioligand [11C]MNPA and antagonist radioligand [11C]Raclopride
    Finnema, S. J.
    Bang-Andersen, B.
    Farde, L.
    Gulyas, B.
    Wikstrom, H. V.
    Halldin, C.
    EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2006, 33 : S211 - S211
  • [46] VARIABILITY IN D-2-DOPAMINE RECEPTOR DENSITY AND AFFINITY - A PET STUDY WITH [C-11] RACLOPRIDE IN MAN
    FARDE, L
    HALL, H
    PAULI, S
    HALLDIN, C
    SYNAPSE, 1995, 20 (03) : 200 - 208
  • [47] QUANTIFICATION OF DOPAMINE D2 RECEPTOR DENSITY AND APPARENT AFFINITY CAN BE USED TO LONGITUDINALLY ASSESS TRANSIENT STRIATAL VARIATIONS DURING ADOLESCENCE USING [11C]RACLOPRIDE PET IMAGING
    Callaghan, P.
    Sobbi, P. Faizi
    Safavi-Naeini, M.
    Wimberley, C.
    Davis, E.
    Zahra, D.
    Arthur, A.
    Rahardjo, G.
    Perkins, G.
    Pascali, G.
    Reilhac-Laborde, A.
    Gregoire, M. C.
    INTERNAL MEDICINE JOURNAL, 2017, 47 : 19 - 19
  • [48] The Dopamine Stabilizer (-)-OSU6162 Occupies a Subpopulation of Striatal Dopamine D2/D3 Receptors: An [11C] Raclopride PET Study in Healthy Human Subjects
    Tolboom, Nelleke
    Berendse, Henk W.
    Leysen, Josee E.
    Yaqub, Maqsood
    van Berckel, Bart N. M.
    Schuit, Robert C.
    Ponsen, Mirthe M.
    Bakker, Esther
    Hoetjes, Nikie J.
    Windhorst, Albert D.
    Carlsson, Maria L.
    Lammertsma, Adriaan A.
    Carlsson, Arvid
    NEUROPSYCHOPHARMACOLOGY, 2015, 40 (02) : 472 - 479
  • [49] The Dopamine Stabilizer (−)-OSU6162 Occupies a Subpopulation of Striatal Dopamine D2/D3 Receptors: An [11C]Raclopride PET Study in Healthy Human Subjects
    Nelleke Tolboom
    Henk W Berendse
    Josee E Leysen
    Maqsood Yaqub
    Bart NM van Berckel
    Robert C Schuit
    Mirthe M Ponsen
    Esther Bakker
    Nikie J Hoetjes
    Albert D Windhorst
    Maria L Carlsson
    Adriaan A Lammertsma
    Arvid Carlsson
    Neuropsychopharmacology, 2015, 40 : 472 - 479
  • [50] 18F-Desmethoxyfallypride and PET is an alternative to 11C raclopride in characterizing D2 receptors in the different Parkinson syndromes
    Vogt, T
    Schreckenberger, M
    Siessmeier, T
    Roesch, F
    Hägele, S
    MOVEMENT DISORDERS, 2005, 20 : S145 - S146