Novel Rho Kinase Inhibitors Are Potent and Efficacious Anti-Inflammatory Agents: An Emerging Role for Rho Kinase 1

被引：0
|
作者：
Fulcher, E. [1 ]
Herbold, M. [1 ]
Brown, A. [1 ]
Pelz, N. [1 ]
Slade, D. [1 ]
Lampe, J. [1 ]
Navratil, T. [1 ]
机构：
[1] Inspire, Durham, NC USA
来源：
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE | 2009年 / 179卷
关键词：
D O I：
暂无
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
A1332
引用
下载
收藏
页数：1
相关论文
共 50 条
  • [11] Chroman-3-amides as potent Rho kinase inhibitors
    Chen, Yen Ting
    Bannister, Thomas D.
    Weiser, Amiee
    Griffin, Evelyn
    Lin, Li
    Ruiz, Claudia
    Cameron, Michael D.
    Schurer, Stephan
    Duckett, Derek
    Schroter, Thomas
    LoGrasso, Philip
    Feng, Yangbo
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2008, 18 (24) : 6406 - 6409
  • [12] Biochemical, Cellular, and Anti-Inflammatory Properties of a Potent, Selective, Orally Bioavailable Benzamide Inhibitor of Rho Kinase Activity
    Rajagopalan, Lakshman E.
    Davies, Michael S.
    Kahn, Larry E.
    Kornmeier, Christine M.
    Shimada, Hideaki
    Steiner, Toni A.
    Zweifel, Ben S.
    Wendling, Jay M.
    Payne, Maria A.
    Loeffler, Richard F.
    Case, Brenda L.
    Norton, Monica B.
    Parikh, Mihir D.
    Nemirovskiy, Olga V.
    Mourey, Robert J.
    Masferrer, Jaime L.
    Misko, Thomas P.
    Kolodziej, Stephen A.
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 2010, 333 (03): : 707 - 716
  • [13] Potent and selective RHO kinase inhibitors: Hit to lead account
    Prokopowicz, Anthony S., III
    Wu, Frank
    Cywin, Charles L.
    Snow, Roger J.
    Hickey, Eugene R.
    Kashem, Mohammed A.
    Shih, Cheng-Kong
    Kerr, Steve
    Jakes, Scott
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2009, 238
  • [14] Rho Kinase Inhibition by Fasudil Has Anti-inflammatory Effects in Hypercholesterolemic Rats
    Ma, Zhihong
    Zhang, Jianping
    Du, Rongpin
    Ji, Ensheng
    Chu, Li
    BIOLOGICAL & PHARMACEUTICAL BULLETIN, 2011, 34 (11) : 1684 - 1689
  • [15] Rho-Kinase Inhibitors as Emerging Targets for Glaucoma Therapy
    Wang, Jun
    Wang, Hanke
    Dang, Yalong
    OPHTHALMOLOGY AND THERAPY, 2023, 12 (06) : 2943 - 2957
  • [16] Rho-Kinase Inhibitors as Emerging Targets for Glaucoma Therapy
    Jun Wang
    Hanke Wang
    Yalong Dang
    Ophthalmology and Therapy, 2023, 12 (6) : 2943 - 2957
  • [17] Rho kinase inhibitors: A novel therapeutical intervention in asthma?
    Schaafsma, Dedmer
    Gosens, Reinoud
    Zaagsma, Johan
    Halayko, Andrew J.
    Meurs, Herman
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2008, 585 (2-3) : 398 - 406
  • [18] The Role of Rho Kinase Inhibitors in Corneal Endothelial Dysfunction
    Okumura, Naoki
    Kinoshita, Shigeru
    Koizumi, Noriko
    CURRENT PHARMACEUTICAL DESIGN, 2017, 23 (04) : 660 - 666
  • [19] MEDI 352-Discovery of novel FMS kinase inhibitors as anti-inflammatory agents
    Meegalla, Sanath K.
    Illig, Carl R.
    Chen, Jinsheng
    Wall, Mark J.
    Wilson, Kenneth J.
    Ballentine, Shelley K.
    Rudolph, M. Jonathan
    DesJarlais, Renee L.
    Chan, Yanmin
    Schubert, Carsten
    Petrounia, Ioanna
    Crysler, Carl S.
    Molloy, Christopher J.
    Chaikin, Margery A.
    Manthey, Carl L.
    Player, Mark R.
    Tomczuk, Bruce E.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2008, 236
  • [20] Rho Kinase Inhibitors as a Novel Treatment for Glaucoma and Ocular Hypertension
    Tanna, Angelo P.
    Johnson, Mark
    OPHTHALMOLOGY, 2018, 125 (11) : 1741 - 1756
12345