Affinity prediction for substrates of the peptide transporter PepT1

被引：23
|
作者：
Bailey, PD
Boyd, CAR
Collier, ID
George, JP
Kellett, GL
Meredith, D
Morgan, KM
Pettecrew, R
Price, RA
机构：
[1] Univ Manchester, Sch Chem, Manchester M60 1QD, Lancs, England
[2] Univ Oxford, Dept Human Anat & Genet, Oxford OX1 3QX, England
[3] Heriot Watt Univ, Sch EPS Chem, Edinburgh EH14 4AS, Midlothian, Scotland
[4] Univ York, Dept Biol, York YO10 5YW, N Yorkshire, England
来源：
CHEMICAL COMMUNICATIONS | 2006年 / 03期
关键词：
D O I：
10.1039/b511996k
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A quantitative method has been developed for determining the affinity of substrates for the peptide transporter PepT1, allowing oral availability of drugs via PepT1 to be estimated.
引用
收藏
页码：323 / 325
页数：3
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