GREEN SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NOVEL 6-ARYL-14H-[1,8] NAPHTHYRIDINO [2′,3′: 4,5] PYRIMIDO [1,2-α] [1,8] NAPHTHYRIDIN-14-ONES

被引：0

作者：

Mogilaiah, K. ^{[1
]}

Reddy, Ch. Thirupati ^{[1
]}

Reddy, N. Vasudeva ^{[1
]}

机构：

[1] Kakatiya Univ, Dept Chem, Warangal 506009, Andhra Pradesh, India

来源：

INDIAN JOURNAL OF HETEROCYCLIC CHEMISTRY | 2012年 / 22卷 / 02期

关键词：

ORGANIC-SYNTHESIS; SOLID SUPPORT; AGENTS;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and rapid method for the synthesis of 6-aryl-14H-[1,8] naphthyridino [2',3' : 4,5] pyrimido [1,2-alpha] [1,8] naphthyridin-14-ones 3 is achieved by the reaction of 3-aryl-2-chloro-1,8-naphthyridines 1 with 2-amino-1,8-naphthyridine-3-carboxylic acid 2 in the presence of catalytic amount of DMF in solvent-free conditions under microwave irradiation. The yields are very good and purity is high. The structural assignments of compounds 3 are based on their elemental analyses and spectral (IR and H-1 NMR) data. The compounds 3 have been tested for their antibacterial activity.

引用

页码：177 / 180

页数：4

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