Paget's disease of bone: Diagnostic and therapeutic updates

被引:1
|
作者
Alaya, R. [1 ]
Alaya, Z. [2 ]
Nang, M. [1 ]
Bouajina, E. [2 ]
机构
[1] Ctr Hosp Sud Francilien, Serv Rhumatol, F-91100 Corbeil Essonnes, France
[2] Hop Farhat Hached, Serv Rhumatol, Ave Ibn El Jazzar, Sousse 4000, Tunisia
来源
REVUE DE MEDECINE INTERNE | 2018年 / 39卷 / 03期
关键词
Paget's disease of bone; SQSTM1; gene; Radiography; Bone fractures; Sarcomatous degeneration; Bisphosphonates; ZOLEDRONIC ACID; SINGLE INFUSION; PREVALENCE; MANAGEMENT; EPIDEMIOLOGY; SQSTM1; AGE;
D O I
10.1016/j.revmed.2017.05.010
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Paget's disease of bone is the second most common metabolic bone disease after osteoporosis. Its pathogenesis is not yet clearly understood. Geographic distribution and epidemiological variations suggest a role of genetic and environmental factors in its pathophysiology. The frequency of the Paget's disease of bone increases with age. Its discovery can be fortuitous. Prognosis mainly depends on the occurrence of complications involving bones and joints, neurological, cardiovascular or metabolic systems. Treatment of symptomatic forms currently relies on bisphosphonates that have transformed its prognosis. (C) 2017 Societe Nationale Francaise de Medecine Interne (SNFMI). Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:185 / 191
页数:7
相关论文
共 50 条
  • [31] Bone Quality in Paget's Disease of Bone
    Singer, Frederick R.
    [J]. CURRENT OSTEOPOROSIS REPORTS, 2016, 14 (02): : 39 - 42
  • [32] Dickkopf-1 as a potential therapeutic target in Paget's disease of bone
    McCarthy, Helen S.
    Marshall, Michael J.
    [J]. EXPERT OPINION ON THERAPEUTIC TARGETS, 2010, 14 (02) : 221 - 230
  • [33] Paget's bone disease in a nonendemic region: Exploring novel therapeutic strategies
    Razavianzadeh, Nasrin
    Shahramirad, Soheil
    Hasani, Mohammad
    Babaei, Hessamedin
    [J]. CLINICAL CASE REPORTS, 2024, 12 (09):
  • [34] Periodontal disease in Paget's disease of bone
    Nuti, Niccolo
    Ferrari, Marco
    [J]. CLINICAL CASES IN MINERAL AND BONE METABOLISM, 2015, 12 (02) : 195 - 198
  • [35] Paget's Disease of Bone: A Disease of the Osteoclast
    Reddy S.V.
    Kurihara N.
    Menaa C.
    Roodman G.D.
    [J]. Reviews in Endocrine and Metabolic Disorders, 2001, 2 (2) : 195 - 201
  • [36] Paget's disease of bone or osteopetrosis?
    Rozin, Alexander
    Bar-Shalom, Rachel
    Ish-Shalom, Sofia
    [J]. CLINICAL RHEUMATOLOGY, 2006, 25 (04) : 544 - 547
  • [37] Is Paget’s disease of bone disappearing?
    T. Cundy
    [J]. Skeletal Radiology, 2006, 35 : 350 - 351
  • [38] Paget's disease of the bone - Reply
    Zargar, AH
    Laway, BA
    Masoodi, SR
    Wani, AI
    Bashir, MI
    Tramboo, NA
    Khan, FA
    [J]. SAUDI MEDICAL JOURNAL, 2000, 21 (04) : 404 - 405
  • [39] Osteocytes and Paget's Disease of Bone
    Tenshin, Hirofumi
    Delgado-Calle, Jesus
    Windle, Jolene J.
    Roodman, G. David
    Chirgwin, John M.
    Kurihara, Noriyoshi
    [J]. CURRENT OSTEOPOROSIS REPORTS, 2024, 22 (02) : 266 - 272
  • [40] IS PAGET'S BONE DISEASE IN RETIREMENT?
    Sanchez, Ariel
    [J]. REVISTA MEDICA DE ROSARIO, 2020, 86 (02): : 98 - 99