Utility of 18F-Fluciclovine PET/CT for Detecting Prostate Cancer Recurrence in Patients With Low (< 1 ng/mL) or Very Low (< 0.3 ng/mL) Prostate-Specific Antigen Levels

被引：8
|
作者：
Wang, Yingbing [1 ]
Chow, David Z. [1 ]
Ebert, Emily [1 ]
Tajmir, Shahein [1 ]
Scott, James A. [1 ]
Palmer, Edwin L. [1 ]
机构：
[1] Massachusetts Gen Hosp, Dept Radiol, 55 Fruit St,Wht 4-427, Boston, MA 02114 USA
来源：
AMERICAN JOURNAL OF ROENTGENOLOGY | 2020年 / 215卷 / 04期
关键词：
biochemical recurrence; fluciclovine PET; prostate cancer; C-11-CHOLINE PET/CT; RELAPSE; TOMOGRAPHY; F-18-FACBC;
D O I：
10.2214/AJR.19.22180
中图分类号：
R8 [特种医学]; R445 [影像诊断学];
学科分类号：
1002 ; 100207 ; 1009 ;
摘要：
OBJECTIVE. We reviewed a retrospective series of 126 F-18-fluciclovine PET/CT studies of patients with biochemically recurrent prostate cancer at low (< 1 ng/mL) and very low (< 0.3 ng/mL) prostate-specific antigen (PSA) levels. CONCLUSION. The rate of PET/CT positivity was 33% (15/46) in patients with low PSA levels and 0% (0/17) in patients with very low PSA levels. Our results suggest that F-18-fluciclovine PET/CT can be helpful for localizing recurrence in patients with PSA levels between 0.3 and 1 ng/mL and that F-18-fluciclovine PET/CT is not recommended in patients with PSA levels less than 0.3 ng/mL.
引用
收藏
页码：997 / 1001
页数：5
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