Targeting cancer with PI3K pathway inhibitors: who to aim at?

被引:2
|
作者
Kinross, Kathryn M. [1 ,4 ]
Sheppard, Karen E. [1 ,3 ]
Pearson, Richard B. [1 ,3 ,4 ]
Phillips, Wayne A. [1 ,2 ,3 ,4 ,5 ]
机构
[1] Peter MacCallum Canc Ctr, Canc Res Div, East Melbourne, Vic, Australia
[2] Peter MacCallum Canc Ctr, Canc Surg Div, East Melbourne, Vic, Australia
[3] Univ Melbourne, Dept Biochem & Mol Biol, Parkville, Vic 3052, Australia
[4] Univ Melbourne, Sir Peter MacCallum Dept Oncol, Parkville, Vic 3052, Australia
[5] Monash Univ, Dept Biochem & Mol Biol, Clayton, Vic, Australia
关键词
D O I
10.3978/j.issn.2218-676X.2012.03.06
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
引用
收藏
页码:119 / 121
页数:3
相关论文
共 50 条
  • [31] Sensitivity of endometrial cancer cells to inhibitors targeting different nodes of the PI3K pathway and their combination with a MEK inhibitor
    Wongchenko, Matthew J.
    Guan, Yinghui
    Wagle, Marie-Claire
    Ryner, Lisa
    Lu, Shan
    Koeppen, Hartmut
    Hampton, Garret
    Lackner, Mark
    Wang, Yulei
    Yan, Yibing
    CANCER RESEARCH, 2013, 73 (08)
  • [32] Multipoint targeting of the PI3K/mTOR pathway in mesothelioma
    S Zhou
    L Liu
    H Li
    G Eilers
    Y Kuang
    S Shi
    Z Yan
    X Li
    J M Corson
    F Meng
    H Zhou
    Q Sheng
    J A Fletcher
    W-B Ou
    British Journal of Cancer, 2014, 110 : 2479 - 2488
  • [33] Targeting PI3K/AKT signaling pathway in obesity
    Savova, Martina S.
    Mihaylova, Liliya, V
    Tews, Daniel
    Wabitsch, Martin
    Georgiev, Milen I.
    BIOMEDICINE & PHARMACOTHERAPY, 2023, 159
  • [34] Targeting colorectal cancer lung metastasis microenvironment with PI3K inhibitors and chemotherapy
    Rychahou, Piotr
    Bae, Younsoo
    Reichel, Derek A.
    Zaytseva, Yekaterina
    Lee, Eun Y.
    Weiss, Heidi L.
    Evers, B. Mark
    CANCER RESEARCH, 2017, 77
  • [35] Targeting PI3K
    Cantley, L.
    Lewis, C. Cantley
    CANCER RESEARCH, 2012, 72
  • [36] Predictive, preventive, and personalized medicine in breast cancer: targeting the PI3K pathway
    Tufail, Muhammad
    Hu, Jia-Ju
    Liang, Jie
    He, Cai-Yun
    Wan, Wen-Dong
    Huang, Yu-Qi
    Jiang, Can-Hua
    Wu, Hong
    Li, Ning
    JOURNAL OF TRANSLATIONAL MEDICINE, 2024, 22 (01)
  • [37] Targeting the PI3K/AKT/mTOR pathway: potential for lung cancer treatment
    Cheng, Haiying
    Shcherba, Marina
    Pendurti, Gopichand
    Liang, Yuanxin
    Piperdi, Bilal
    Perez-Soler, Roman
    LUNG CANCER MANAGEMENT, 2014, 3 (01) : 67 - 75
  • [38] Targeting the PI3K pathway in HER2-positive gastric cancer
    Toomey, S.
    Farrelly, A. M.
    Mezynski, M. J.
    Carr, A.
    Armstrong, P.
    Mcauley, J.
    Fay, J.
    Kay, E. W.
    Cremona, M.
    Holohan, C.
    Keegan, N. M.
    Elamin, Y.
    Rafee, S.
    Hennessy, B. T.
    EUROPEAN JOURNAL OF CANCER, 2018, 103 : E142 - E142
  • [39] Marine compounds targeting the PI3K/Akt signaling pathway in cancer therapy
    Wei, Jiaen
    Gou, Zhanping
    Wen, Ying
    Luo, Qiaohong
    Huang, Zunnan
    BIOMEDICINE & PHARMACOTHERAPY, 2020, 129
  • [40] Predictive, preventive, and personalized medicine in breast cancer: targeting the PI3K pathway
    Muhammad Tufail
    Jia-Ju Hu
    Jie Liang
    Cai-Yun He
    Wen-Dong Wan
    Yu-Qi Huang
    Can-Hua Jiang
    Hong Wu
    Ning Li
    Journal of Translational Medicine, 22