A reagentless and reusable electrochemical DNA sensor based on target hybridization-induced stem-loop probe formation

被引：50
|
作者：
Yu, Zhi-gang [1 ,2 ]
Lai, Rebecca Y. [1 ]
机构：
[1] Univ Nebraska, Lincoln, NE 68588 USA
[2] Harbin Univ Sci & Technol, Key Lab Green Chem Engn & Technol, Coll Heilongjiang Prov, Coll Chem & Environm Engn, Harbin 150040, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 85期
基金：
美国国家科学基金会;
关键词：
OLIGONUCLEOTIDES; VOLTAMMETRY; BIOSENSORS; BLOOD; FILMS;
D O I：
10.1039/c2cc35985e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report a reagentless and reusable electrochemical DNA sensor that exploits competitive binding and target hybridization-induced change in the signalling probe conformation for robust detection of a target DNA sequence.
引用
收藏
页码：10523 / 10525
页数：3
相关论文
共 32 条
  • [31] Target-induced formation of gold amalgamation on DNA-based sensing platform for electrochemical monitoring of mercury ion coupling with cycling signal amplification strategy
    Chen, Jinfeng
    Tang, Juan
    Zhou, Jun
    Zhang, Lan
    Chen, Guonan
    Tang, Dianping
    ANALYTICA CHIMICA ACTA, 2014, 810 : 10 - 16
  • [32] Label-free fluorescent bio sensor based on the target recycling and Thioflavin T-induced quadruplex formation for short DNA species of c-erbB-2 detection
    Chen, Jinghua
    Lin, Jia
    Zhang, Xi
    Cai, Shuxian
    Wu, Dongzhi
    Li, Chunyan
    Yang, Sheng
    Zhang, Jing
    ANALYTICA CHIMICA ACTA, 2014, 817 : 42 - 47
1234