A reagentless and reusable electrochemical DNA sensor based on target hybridization-induced stem-loop probe formation

被引：50
|
作者：
Yu, Zhi-gang [1 ,2 ]
Lai, Rebecca Y. [1 ]
机构：
[1] Univ Nebraska, Lincoln, NE 68588 USA
[2] Harbin Univ Sci & Technol, Key Lab Green Chem Engn & Technol, Coll Heilongjiang Prov, Coll Chem & Environm Engn, Harbin 150040, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2012年 / 48卷 / 85期
基金：
美国国家科学基金会;
关键词：
OLIGONUCLEOTIDES; VOLTAMMETRY; BIOSENSORS; BLOOD; FILMS;
D O I：
10.1039/c2cc35985e
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
We report a reagentless and reusable electrochemical DNA sensor that exploits competitive binding and target hybridization-induced change in the signalling probe conformation for robust detection of a target DNA sequence.
引用
收藏
页码：10523 / 10525
页数：3
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