Orally administered TQ-A3334 to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics single and multiple ascending doses in healthy Chinese subjects

被引：0
|
作者：
Hu, Yue [1 ]
Zhang, Hong [1 ]
Wu, Min [1 ]
Huo, Dandan [2 ]
Chen, Hong [1 ]
Li, Xiaojiao [1 ]
Xu, Zhongnan [2 ]
Ding, Yanhua [1 ]
Niu, Junqi [3 ]
机构：
[1] Jilin Univ, Phase Clin Res Ctr 1, Hosp 1, Changchun, Jilin, Peoples R China
[2] Chiatai Tianqing Pharmaceut Co Ltd, Changchun, Jilin, Peoples R China
[3] Jilin Univ, Hosp 1, Changchun, Jilin, Peoples R China
来源：
JOURNAL OF HEPATOLOGY | 2019年 / 70卷 / 01期
关键词：
D O I：
10.1016/S0618-8278(19)30921-1
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
FRI-176
引用
收藏
页码：E466 / E467
页数：2
相关论文
共 50 条
  • [21] Safety, tolerability, pharmacokinetics, and pharmacodynamics of multiple doses of apixaban in healthy Japanese male subjects
    Yamahira, Naomi
    Frost, Charles
    Fukase, Hiroyuki
    Yu, Zhigang
    Wang, Jessie
    Pursley, Janice
    LaCreta, Frank
    Hiraoka, Masaki
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2014, 52 (07) : 564 - 573
  • [22] Pharmacokinetics, safety, and tolerability of single and multiple-doses of pinocembrin injection administered intravenously in healthy subjects
    Cao, Guoying
    Ying, Pengyue
    Yan, Bei
    Xue, Wei
    Li, Kexin
    Shi, Aixin
    Sun, Taohua
    Yan, Jiling
    Hu, Xin
    JOURNAL OF ETHNOPHARMACOLOGY, 2015, 168 : 31 - 36
  • [23] Safety, tolerability, pharmacokinetics and pharmacodynamics of high single-ascending doses of ticagrelor in healthy volunteers
    Teng, Renli
    Butler, Kathleen
    INTERNATIONAL JOURNAL OF CLINICAL PHARMACOLOGY AND THERAPEUTICS, 2013, 51 (10) : 795 - 806
  • [24] Pharmacokinetics, safety, and tolerability of ascending single doses of moxifloxacin, a new 8-methoxy quinolone, administered to healthy subjects
    Stass, H
    Dalhoff, A
    Kubitza, D
    Schühly, U
    ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1998, 42 (08) : 2060 - 2065
  • [25] Pharmacokinetics and pharmacodynamics of single and multiple doses of prasugrel in healthy native Chinese subjects
    Cui, Yi-min
    Wang, Zi-ning
    Chen, Xiao-wen
    Zhang, Hui-lin
    Zhao, Xia
    Zhou, Ying
    ACTA PHARMACOLOGICA SINICA, 2012, 33 (11) : 1395 - 1400
  • [26] Pharmacokinetics and pharmacodynamics of single and multiple doses of prasugrel in healthy native Chinese subjects
    Yi-min Cui
    Zi-ning Wang
    Xiao-wen Chen
    Hui-lin Zhang
    Xia Zhao
    Ying Zhou
    Acta Pharmacologica Sinica, 2012, 33 : 1395 - 1400
  • [27] Safety, tolerability, and pharmacokinetics of raltegravir after single and multiple doses in healthy subjects
    Iwamoto, M.
    Wenning, L. A.
    Petry, A. S.
    Laethem, M.
    De Smet, M.
    Kost, J. T.
    Merschman, S. A.
    Strohmaier, K. M.
    Ramael, S.
    Lasseter, K. C.
    Stone, J. A.
    Gottesdiener, K. M.
    Wagner, J. A.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2008, 83 (02) : 293 - 299
  • [28] Safety, tolerability and pharmacokinetics after single and multiple doses of preladenant (SCH420814) administered in healthy subjects
    Cutler, D. L.
    Tendolkar, A.
    Grachev, I. D.
    JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2012, 37 (05) : 578 - 587
  • [29] Pharmacokinetics, safety, and tolerability of single and multiple-doses of pinocembrin injection administered intravenously in healthy subjects.
    Cao, Guoying
    PHARMACOTHERAPY, 2014, 34 (10): : E221 - E222
  • [30] Safety, tolerability, pharmacokinetics, pharmacodynamics, bioavailability and food effect of single doses of soticlestat in healthy subjects
    Wang, Shining
    Chen, Grace
    Merlo Pich, Emilio
    Affinito, John
    Cwik, Michael
    Faessel, Helene
    BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2021, 87 (11) : 4354 - 4365
12345