Chemical Constituents of the Sponge Mycale Species from South China Sea

被引：0
|
作者：
Zhou, Xuefeng [1 ]
Lin, Xiuping [1 ]
Guo, Xieyang [2 ]
Yang, Bin [1 ]
Yang, Xian-Wen [1 ]
Liu, Yonghong [1 ]
机构：
[1] Chinese Acad Sci, South China Sea Inst Oceanol, Res Ctr Marine Microbes, Guangdong Key Lab Marine Mat Med,Key Lab Marine B, Guangzhou 510301, Guangdong, Peoples R China
[2] Southern Med Univ, Sch Pharmaceut Sci, Guangzhou 510515, Guangdong, Peoples R China
来源：
RECORDS OF NATURAL PRODUCTS | 2013年 / 7卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Sponge Mycale species; Chemical constituents; Brine shrimp lethality test; MARINE SPONGE; STEROLS; METABOLITES;
D O I：
暂无
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Chemical investigation of the sponge Mycale species from the South China Sea afforded eleven known compounds, henicosanoic acid methyl ester (1), hexadecyl ethers of glycerol (2), N-docosanoyl-D-erythro-(2S,3R)-16-methyl-heptadecasphing-4(E)-enine (3), dibutyl phthalate (4), cholesterol (5), 5 alpha,8 alpha-epidioxycholest-6,22-dien-3 beta-ol (6), 5-hexadecyl-pyrrole-2-carboxaldehyde (7), benzoic acid (8), 4-hydroxybenzoic acid (9), thymine (10), and uracil (11) Compounds 1-4, 6-9 were obtained from the sponge of the genus Mycale for the first time, and 4 and 6 showed toxicity in the brine shrimp lethality test with the LD50 values at 2.9 mu g/mL and 4.7 mu g/mL, respectively.
引用
收藏
页码：119 / 123
页数：5
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