Flavone and xanthone derivatives related to fluoroquinolones

被引：9
|
作者：
Mari, S
Rossi, M
Valenti, P
Da Re, P
机构：
[1] Univ Milan, Inst Pharmaceut Chem, I-20131 Milan, Italy
[2] Univ Bologna, Dept Pharmaceut Sci, I-40126 Bologna, Italy
来源：
FARMACO | 1999年 / 54卷 / 06期
关键词：
flavone; xanthen-9-one; fluoroquinolones; cytotoxicity; antimicrobial activity;
D O I：
10.1016/S0014-827X(99)00047-6
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
A number of flavone and xanthone derivatives bearing some characteristic features of fluoroquinolones such as the fluorine atom and an ortho piperazine ring are described. The new compounds have been tested for possible cytotoxic and antimicrobial activities. Cytotoxicity of both groups of compounds is rather poor, while the antibacterial activity is restricted to xanthones. (C) 1999 Elsevier Science S.A. All rights reserved.
引用
收藏
页码：411 / 415
页数：5
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