Reversal of pulmonary hypertension associated with plexiform lesions in congenital heart disease: A case report

被引：12
|
作者：
Epting, CL
Wolfe, RR
Abman, SH
Deutsch, GH
Ivy, D
机构：
[1] Childrens Hosp, Pediat Heart Lung Ctr, Pediat Cardiol Sect, Denver, CO 80218 USA
[2] Childrens Hosp, Pediat Heart Lung Ctr, Sect Pulmonol, Denver, CO 80218 USA
[3] Childrens Hosp, Pediat Heart Lung Ctr, Sect Pathol, Denver, CO 80218 USA
来源：
PEDIATRIC CARDIOLOGY | 2002年 / 23卷 / 02期
关键词：
pulmonary hypertension; congenital heart disease; nitric oxide; atrial natriuretic peptide; patent ductus arteriosus;
D O I：
10.1007/s00246-001-0044-9
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
We describe a 2-year-old child with severe pulmonary hypertension due to a patent ductus arteriosus (PDA) with plexiform lesions on lung biopsy. Despite high basal pulmonary vascular resistance with minimal responsiveness to inhaled nitric oxide and other vasodilators, and advanced plexogenic arteriopathy on lung biopsy, her pulmonary hypertension completely resolved after PDA ligation and during 8 years of follow-up.
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页码：182 / 185
页数：4
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