Two New Eudesmane Sesquiterpenoids from the Flowers of Chrysanthemum indicum

被引：12
|
作者：
Yang, Jun-Li [1 ,2 ]
Liu, Lei-Lei [1 ,2 ]
Shi, Yan-Ping [1 ,2 ]
机构：
[1] Chinese Acad Sci, Lanzhou Inst Chem Phys, CAS Key Lab Chem Northwestern Plant Resources, Lanzhou 730000, Gansu, Peoples R China
[2] Chinese Acad Sci, Lanzhou Inst Chem Phys, Key Lab Nat Med Gansu Prov, Lanzhou 730000, Gansu, Peoples R China
来源：
NATURAL PRODUCTS AND BIOPROSPECTING | 2019年 / 9卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Chrysanthemum indicum; Sesquiterpenoids; Eudesmane; RHIZOMES;
D O I：
10.1007/s13659-019-0199-9
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The flowers of Chrysanthemum indicum, i.e. Ye-ju-hua recorded in the Chinese Pharmacopoeia, has been widely used in China as an important heat-clearing and detoxifying herb for the treatment of inflammation, headache, and vertigo. A phytochemical investigation of this herb has led to the isolation of two new eudesmane sesquiterpenoids, 7-epi-eudesm-4(15),11(13)-diene-1 beta,3 beta-diol (1) and 7-epi-1 beta-hydroxy-beta-eudesmol (2). The molecular structures of these new sesquiterpenoids were established based on the comprehensive spectroscopic analyses, including NMR, MS, and IR, and comparing with the literatures. [GRAPHICS] .
引用
收藏
页码：145 / 148
页数：4
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