Catalyst-free synthesis of functionalized dihydro-2-oxypyrroles by the reaction of enaminones and N,N′-bis(phenylmethylidene) phenylmethane

被引:5
|
作者
Alizadeh, Abdolali [1 ]
Mokhtari, Javad [1 ]
Zhu, Long-Guan [2 ]
机构
[1] Tarbiat Modares Univ, Dept Chem, Tehran, Iran
[2] Zhejiang Univ, Dept Chem, Hangzhou 310027, Zhejiang, Peoples R China
关键词
Primary amine; Dialkyl acetylenedicarboxylate; N; '-bis(phenylmethylidene)phenylmethane; Dihydro-2-oxypyrrole; Three-component reaction; AROMATIC-ALDEHYDES; ALKALOIDS;
D O I
10.1016/j.crci.2013.01.020
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
A catalyst-free and convenient approach for the preparation of substituted dihydro-2-oxypyrrole is described. This three-component reaction between primary amines, dialkyl acetylenedicarboxylate, and N,N'-bis(phenylmethylidene)phenylmethane proceeds in MeOH under reflux conditions in good to excellent yields. (C) 2013 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:863 / 867
页数:5
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