Effect of EDA/PEGDGE mole ratios on PEG-based Hydrogel Scaffolds Properties

被引：3
|
作者：
Hamid, Zuratul Ain Abdul [1 ]
Blencowe, Anton [2 ]
Qiao, Greg [2 ]
Stevens, Geoff [2 ]
机构：
[1] Univ Sains Malaysia, Sch Mat & Mineral Resources Engn, Engn Campus,14300 Nibong Tebal, Pulau, Pinang, Malaysia
[2] Univ Melbourne, Dept Chem & Biomol Engn, Victoria 3010, Australia
来源：
ADVANCED MATERIALS ENGINEERING AND TECHNOLOGY | 2012年 / 626卷
关键词：
hydrogel scaffolds; epoxy-amine step growth polymerization; tissue engineering; cross-linked hydrogel; TISSUE-ENGINEERING APPLICATIONS; POLY(ETHYLENE GLYCOL); BIODEGRADABLE HYDROGELS; POLYETHYLENE-GLYCOL; COPOLYMERS;
D O I：
10.4028/www.scientific.net/AMR.626.681
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
The synthesis of biocompatible hydrogel based on poly(ethylene glycol) (PEG) and ethylene diamine (EDA) using epoxy-amine chemistry was conducted. PEG was chosen as the base material (or monomer) to synthesise hydrogels in this study due to its high hydrophilicity, biocompatibility and low toxicity properties. The effects of mole ratios of EDA to PEGDGE on the hydrogel scaffolds properties (i.e., gelling time, swelling) were investigated. It was found out for hydrogel scaffolds prepared at 1.2 and 1.4 M [PEGDGE] and an EDA/PEGDGE mol ratio of 0.5 in DMSO gave the optimum hydrogel properties. Swelling studies has confirmed that hydrogel prepared at 0.5 mole ratios consist of highly cross-linked network as expected.
引用
收藏
页码：681 / +
页数：2
相关论文
共 50 条
  • [1] In vivo Studies of Biocompatible PEG-based Hydrogel Scaffolds Modified with Biofactors
    Hamid, Zuratul Ain Abdul
    Blencowe, Anton
    Ozcelik, Berkay
    Qiao, Greg
    Stevens, Geoff
    Palmer, Jason
    Abberton, Eighth Keren M.
    Morrison, Wayne A.
    Penington, Anthony K. J.
    2014 IEEE CONFERENCE ON BIOMEDICAL ENGINEERING AND SCIENCES (IECBES), 2014, : 260 - 264
  • [2] PEG-based hydrogel membrane coatings
    Sagle, Alyson C.
    Ju, Hao
    Freeman, Benny D.
    Sharma, Mukul M.
    POLYMER, 2009, 50 (03) : 756 - 766
  • [3] Photoimmobilization of organophosphorus hydrolase within a PEG-based hydrogel
    Andreopoulos, FM
    Roberts, MJ
    Bentley, MD
    Harris, JM
    Beckman, EJ
    Russell, AJ
    BIOTECHNOLOGY AND BIOENGINEERING, 1999, 65 (05) : 579 - 588
  • [4] A PEG-Based Hydrogel for Effective Wound Care Management
    Chen, Sen-Lu
    Fu, Ru-Huei
    Liao, Shih-Fei
    Liu, Shih-Ping
    Lin, Shinn-Zong
    Wang, Yu-Chi
    CELL TRANSPLANTATION, 2018, 27 (02) : 275 - 284
  • [5] PEG-based hydrogel synthesis via the photodimerization of anthracene groups
    Zheng, YJ
    Mieie, M
    Mello, SV
    Mabrouki, M
    Andreopoulos, FM
    Konka, V
    Pham, SM
    Leblanc, RM
    MACROMOLECULES, 2002, 35 (13) : 5228 - 5234
  • [6] PEG-Based Hydrogel Coatings: Design Tools for Biomedical Applications
    Wancura, Megan
    Nkansah, Abbey
    Robinson, Andrew
    Toubbeh, Shireen
    Talanker, Michael
    Jones, Sarah
    Cosgriff-Hernandez, Elizabeth
    ANNALS OF BIOMEDICAL ENGINEERING, 2024, 52 (07) : 1804 - 1815
  • [7] Development of colorimetric PEG-based hydrogel sensors for urea detection
    Efstathiou, Spyridon
    Wemyss, Alan M.
    Coursari, Despina
    Hand, Rachel A.
    Tinley, Emmett Cullen
    Ford, Jane
    Edwards, Stephanie E.
    Bates, Susan
    Evans, Richard L.
    Khoshdel, Ezat
    Haddleton, David M.
    SOFT MATTER, 2025, 21 (12) : 2268 - 2281
  • [8] Tailoring the properties of PDMS-PEG hydrogel scaffolds
    Bailey, Brennan M.
    Hui, Vivian
    Fei, Ruochong
    Grunlan, Melissa A.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2012, 243
  • [9] Mechanical and tribological characterisations of PEG-based hydrogel coatings on XLPE surfaces
    Xu, Dichu
    Harvey, Terry
    Martinez, Janire
    Begiristain, Eider
    Dominguez-Trujillo, Cristina
    Sanchez-Abella, Laura
    Browne, Martin
    Cook, Richard B.
    WEAR, 2023, 522
  • [10] PEG-based 3D hydrogel slide shows promise
    不详
    FUTURE MEDICINAL CHEMISTRY, 2009, 1 (07) : 1208 - 1208
12345