Dynamic combinatorial libraries constructed on polymer scaffolds

被引：39
|
作者：
Fulton, David A. [1 ]
机构：
[1] Univ Newcastle Upon Tyne, Sch Chem, Newcastle Upon Tyne NE1 7RU, Tyne & Wear, England
来源：
ORGANIC LETTERS | 2008年 / 10卷 / 15期
关键词：
D O I：
10.1021/ol8011309
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Functionalized polymers were prepared by grafting acylhydrazides onto a polyvinylbenzaldehyde scaffold through reversible hydrazone linkages. The dynamic nature of these linkages allows the functionalized polymers to exchange and reshuffle their appendages, and the resultant mixture of polymers can be considered as a dynamic combinatorial library constructed upon a polymer scaffold. The dynamic nature of these functionalized polymers was demonstrated.
引用
收藏
页码：3291 / 3294
页数：4
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