Investigation of Multilayered Protein Adsorption on Carbonate Apatite with a QCM Technique

被引：2
|
作者：
Yoshioka, Tomohiko [1 ]
Yonekura, Hiroshi [1 ]
Ikoma, Toshiyuki [1 ]
Tagaya, Motohiro [2 ]
Tanaka, Junzo [1 ]
机构：
[1] Tokyo Inst Technol, Dept Met & Ceram Sci, Meguro Ku, 2-12-1 Ookayama, Tokyo 1528550, Japan
[2] Nagaoka Univ Technol, Dept Mat Sci & Technol, Nagaoka, Niigata 16031, Japan
来源：
BIOCERAMICS 24 | 2013年 / 529-530卷
关键词：
quartz crystal microbalance (QCM); carbonate apatite; protein adsorption; QUARTZ-CRYSTAL MICROBALANCE; CELL-ADHESION; HYDROXYAPATITE; DISSIPATION;
D O I：
10.4028/www.scientific.net/KEM.529-530.74
中图分类号：
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
This study is concerned with multilayered protein adsorption on carbonate apatite (CAp) that is measured with a quartz crystal microbalance (QCM) technique. A carbonate apatite-deposited QCM sensor was prepared by electrophoretic deposition (EPD). On the CAp-deposited QCM sensor, fibrinogen adsorption followed by thrombin adsorption was investigated. The adsorption of fibrinogen on CAp led to a clear decrease in the resonance frequency of the sensor, which means that fibrinogen adsorbed on the CAp-deposited QCM sensor. The adsorbed amount of fibrinogen was larger on CAp than on a pristine sensor (Au). Although successive thrombin adsorption occurred on fibrinogen adlayers on both CAp and Au, the adsorbed amount and its conformation were different depending on the surface.
引用
收藏
页码：74 / +
页数：2
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