Hepatitis C in Pregnancy in the Era of Direct-acting Antiviral Treatment: Potential Benefits of Universal Screening and Antepartum Therapy

被引:18
|
作者
Bernstein, Helene B. [1 ,2 ]
Dunkelberg, Jeffrey C. [3 ]
Leslie, Kimberly K. [4 ]
机构
[1] SUNY Upstate Med Univ, Dept Obstet & Gynecol, Syracuse, NY 13210 USA
[2] SUNY Upstate Med Univ, Dept Microbiol & Immunol, Syracuse, NY 13210 USA
[3] Univ Iowa, Dept Internal Med, Div Gastroenterol & Hepatol, Iowa City, IA 52242 USA
[4] Univ Iowa, Dept Obstet & Gynecol, Div Maternal Fetal Med, Carver Coll Med, Iowa City, IA 52242 USA
来源
CLINICAL OBSTETRICS AND GYNECOLOGY | 2018年 / 61卷 / 01期
关键词
hepatitis C; pregnancy; antiviral agents; antepartum therapy; universal screening; VERTICAL TRANSMISSION; PATIENT POPULATIONS; CLINICAL-RESEARCH; VIRUS-INFECTION; WOMEN; RISK; PREVENTION; DAAS;
D O I
10.1097/GRF.0000000000000345
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Hepatitis C in pregnancy is on the rise, and new direct-acting antiviral agents are available that cure the disease. Published recommendations need to be reviewed and clinically evaluated for the care of pregnant women who are at risk for or have chronic hepatitis C. Available evidence and some of the medical and ethical reasons to consider universal screening and antepartum therapy for hepatitis C during pregnancy are presented. Universal screening and proactive treatment during pregnancy is on the horizon, and these measures should be quickly evaluated for safety and implemented if appropriate.
引用
收藏
页码:146 / 156
页数:11
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