Biomarkers for ectopic pregnancy and pregnancy of unknown location

被引：38
|
作者：
Senapati, Suneeta [1 ]
Barnhart, Kurt T. [1 ]
机构：
[1] Univ Penn, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA
来源：
FERTILITY AND STERILITY | 2013年 / 99卷 / 04期
基金：
美国国家卫生研究院;
关键词：
Ectopic pregnancy; biomarker; pregnancy of unknown location; proteomics; HUMAN CHORIONIC-GONADOTROPIN; SERUM CREATINE-KINASE; ENDOTHELIAL GROWTH-FACTOR; PLASMA PROTEIN-A; LEUKEMIA INHIBITORY FACTOR; TUBAL PREGNANCY; PROGESTERONE MEASUREMENT; ACTIVIN-A; INTRAUTERINE PREGNANCIES; ABNORMAL PREGNANCIES;
D O I：
10.1016/j.fertnstert.2012.11.038
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
Early pregnancy failure is the most common complication of pregnancy, and 1% to 2% of all pregnancies will be ectopic. As one of the leading causes of maternal morbidity and mortality, diagnosing ectopic pregnancy and determining the fate of a pregnancy of unknown location are of great clinical concern. Several serum and plasma biomarkers for ectopic pregnancy have been investigated independently and in combination. The following is a review of the state of biomarker discovery and development for ectopic pregnancy and pregnancy of unknown location. (Fertil Steril (R) 2013;99:1107-16. (C) 2013 by American Society for Reproductive Medicine.)
引用
收藏
页码：1107 / 1116
页数：10
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