Biomarkers for ectopic pregnancy and pregnancy of unknown location

被引：38

作者：

Senapati, Suneeta ^{[1
]}

Barnhart, Kurt T. ^{[1
]}

机构：

[1] Univ Penn, Dept Obstet & Gynecol, Philadelphia, PA 19104 USA

来源：

FERTILITY AND STERILITY | 2013年 / 99卷 / 04期

基金：

美国国家卫生研究院;

关键词：

Ectopic pregnancy; biomarker; pregnancy of unknown location; proteomics; HUMAN CHORIONIC-GONADOTROPIN; SERUM CREATINE-KINASE; ENDOTHELIAL GROWTH-FACTOR; PLASMA PROTEIN-A; LEUKEMIA INHIBITORY FACTOR; TUBAL PREGNANCY; PROGESTERONE MEASUREMENT; ACTIVIN-A; INTRAUTERINE PREGNANCIES; ABNORMAL PREGNANCIES;

D O I：

10.1016/j.fertnstert.2012.11.038

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Early pregnancy failure is the most common complication of pregnancy, and 1% to 2% of all pregnancies will be ectopic. As one of the leading causes of maternal morbidity and mortality, diagnosing ectopic pregnancy and determining the fate of a pregnancy of unknown location are of great clinical concern. Several serum and plasma biomarkers for ectopic pregnancy have been investigated independently and in combination. The following is a review of the state of biomarker discovery and development for ectopic pregnancy and pregnancy of unknown location. (Fertil Steril (R) 2013;99:1107-16. (C) 2013 by American Society for Reproductive Medicine.)

引用

页码：1107 / 1116

页数：10

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