Cycloartane glycosides from Cimicifuga dahurica

被引:17
|
作者
Zhang, QW
Ye, WC
Hsiao, WWL
Zhao, SX
Che, CT [1 ]
机构
[1] Chinese Univ Hong Kong, Sch Chinese Med, Hong Kong 210009, Hong Kong, Peoples R China
[2] Hong Kong Univ Sci & Technol, Dept Biol, Hong Kong, Hong Kong, Peoples R China
[3] China Pharmaceut Univ, Dept Phytochem, Nanjing 210009, Peoples R China
关键词
Cimicifuga dahurica; Ranunculaceae; cycloartane glycoside; trinorcycloartane glycoside;
D O I
10.1248/cpb.49.1468
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
A new cycloartane bisdesmoside and two new trinorcycloartane glycosides, along with four known cycloartane compounds, were isolated from the rhizomes of Cimicifuga dahurica (Ranunculaccae). The structures of the new compounds were elucidated as 3-O-alpha -L-arabinopyranosyl cimigenol 15-O-beta -D-glucopyranoside, 24-hydroxy-12 beta -acetoxy-25,26,27-trinorcycloartan-16,23-dione 3 beta -O-alpha -L-arabinopyranoside, and 16 alpha ,24 alpha -dihydroxy-12 beta -acetoxy-25,26,27-trinor-16,24-cyclocycloartan-23-one 3 beta -O-alpha -L-arabinopyranoside by extensive NMR methods, FAB-MS, and hydrolysis.
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页码:1468 / 1470
页数:3
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