Inadequacy of the current WHO re-treatment regimen in a central Siberian prison: treatment failure and MDR-TB

被引：0
|
作者：
Kimerling, ME
Kluge, H
Vezhnina, N
Iacovazzi, T
Demeulenaere, T
Portaels, F
Matthys, F
机构：
[1] Univ Alabama, Sch Med, Dept Med, Birmingham, AL USA
[2] Med Sans Frontieres, Brussels, Belgium
[3] Colony 33 Med Dept, Mariinsk, Russia
[4] Inst Trop Med, Dept Microbiol, B-2000 Antwerp, Belgium
来源：
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE | 1999年 / 3卷 / 05期
关键词：
tuberculosis; multidrug resistance; prisons;
D O I：
暂无
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
Multidrug-resistant tuberculosis (MDR-TB) threatens the progress of global control efforts. Prisons represent a high risk setting for development and transmission of MDR-TB. In a Siberian TB referral prison (Kemerovo region), the treatment failure rate is 35% (June 1996-March 1997), despite implementation of a strict DOTS program and use of the World Health Organization Category 2 re-treatment regimen for all new cases. Among 164 patients (December 1997-March 1998), initial resistance to isoniazid and rifampin is 22.6%. Such a rate is a warning call to reconsider prison control strategies, and importantly, to address the treatment regimens necessary to combat an institutional epidemic of MDR-TB.
引用
收藏
页码：451 / 453
页数：3
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