A dendritic cell targeting NY-ESO-1 vaccine significantly augments early and durable immune responses in melanoma patients pretreated with human Flt-3 Ligand

被引:0
|
作者
Bhardwaj, Nina [1 ]
Friedlander, Philip [2 ]
Pavlick, Anna [3 ]
Ernstoff, Marc [4 ]
Gastman, Brian [5 ]
Hanks, Brent [6 ]
Albertini, Mark [7 ]
Luke, Jason [8 ]
Yellin, Michael [9 ]
Keler, Tibor [9 ]
Davis, Thomas [9 ]
Vitale, Laura [9 ]
Blazquez, Ana [10 ]
Morishima, Chihiro [11 ]
Danaher, Patrick [12 ]
Warren, Sarah [12 ]
Salim, Bob [13 ]
Hess, Bruce [11 ]
D'Amico, Leonard [11 ]
Lundgren, Lisa [14 ]
Disis, Nora [11 ]
Cheever, Martin [14 ]
Fling, Steven [14 ]
机构
[1] Icahn Sch Med Mt Sinai, New York, NY 10029 USA
[2] Mt Sinai Beth Israel, New York, NY USA
[3] NYU Lagone Med Ctr, New York, NY USA
[4] Roswell Pk Canc Inst, Buffalo, NY USA
[5] Cleveland Clin, Cleveland, OH 44106 USA
[6] Duke, Durham, NC USA
[7] Univ Wisconsin, Madison, WI USA
[8] Univ Chicago Med, Chicago, IL USA
[9] Celldex Therapeut, Needham, MA USA
[10] Mt Sinai, New York, NY USA
[11] Univ Washington, Seattle, WA 98195 USA
[12] Nanostring Technol, Seattle, WA USA
[13] Axio Res, Seattle, WA USA
[14] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA
来源
关键词
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
O5
引用
收藏
页数:2
相关论文
共 43 条
  • [31] LV305, a dendritic cell-targeting integration-deficient ZVex™-based lentiviral vector encoding NY-ESO-1, induces potent anti-tumor immune response
    Albershardt, Tina Chang
    Campbell, David James
    Parsons, Andrea Jean
    Slough, Megan Merrill
    ter Meulen, Jan
    Berglund, Peter
    MOLECULAR THERAPY-ONCOLYTICS, 2016, 3
  • [32] Naturally occurring human lymphocyte antigen-A2 restricted CD8+T-cell response to the cancer testis antigen NY-ESO-1 in melanoma patients
    Valmori, D
    Dutoit, V
    Liénard, D
    Rimoldi, D
    Pittet, MJ
    Champagne, P
    Ellefsen, K
    Sahin, U
    Speiser, D
    Lejeune, F
    Cerottini, JC
    Romero, P
    CANCER RESEARCH, 2000, 60 (16) : 4499 - 4506
  • [33] Murine FLT3 Ligand-Derived Dendritic Cell-Mediated Early Immune Responses Are Critical to Controlling Cell-Free Human T Cell Leukemia Virus Type 1 Infection
    Rahman, Saifur
    Khan, Zafar K.
    Wigdahl, Brian
    Jennings, Stephen R.
    Tangy, Frederic
    Jain, Pooja
    JOURNAL OF IMMUNOLOGY, 2011, 186 (01): : 390 - 402
  • [34] Murine FLT3 ligand-derived dendritic cell-mediated early immune responses are critical to controlling cell-free human T cell leukemia virus type 1 infection
    Saifur Rahman
    Zafar K Khan
    Brian Wigdahl
    Stephen Jennings
    Frederic Tangy
    Pooja Jain
    Retrovirology, 11 (Suppl 1)
  • [35] ANALYSIS OF CD8+T CELL RESPONSES TO AFP, GLYPICAN-3, MAGE-A1 AND NY-ESO-1 IN PATIENTS WITH HEPATOCELLULAR CARCINOMA REVEALS A CLEAR HIERARCHY AND IMMUNODOMINANCE
    Flecken, Tobias
    Neumann-Haefelin, Christoph
    Spangenberg, Hans Christian
    Drognitz, Oliver
    Blum, Hubert E.
    Thimme, Robert
    HEPATOLOGY, 2011, 54 : 965A - 965A
  • [36] ANALYSIS OF CD8+ T-CELL RESPONSES TO AFP, GLYPICAN-3, MAGE-A1 AND NY-ESO-1 IN PATIENTS WITH HEPATOCELLULAR CARCINOMA REVEALS A CLEAR HIERARCHY AND IMMUNODOMINANCE
    Flecken, T.
    Breous, E.
    Neumann-Haefelin, C.
    Spangenberg, H. C.
    Drognitz, O.
    Blum, H. E.
    Thimme, R.
    JOURNAL OF HEPATOLOGY, 2011, 54 : S88 - S88
  • [37] In vivo targeting of a highly conserved HIV-1 envelope peptide-cocktail vaccine to rhesus macaque dendritic cells using Flt3 ligand and CpG oligodeoxynucleotides for inducing cellular immune responses
    Nehete, Pramod N.
    Nehete, Bharti P.
    Whitney, Ian
    Buchl, Stephanie
    Sastry, K. Jagannadha
    JOURNAL OF MEDICAL PRIMATOLOGY, 2006, 35 (4-5) : 309 - 309
  • [38] Murine Flt3L-derived dendritic cell mediated early immune responses are critical to controlling cell-free HTLV-1 infection
    Saifur Rahman
    Zafar K Khan
    Brian Wigdahl
    Stephen R Jennings
    Frederic Tangy
    Pooja Jain
    Retrovirology, 8 (Suppl 1)
  • [39] The programmed cell death protein-1/programmed cell death ligand 1 expression, CD3+T cell infiltration, NY-ESO-1 expression, and microsatellite instability phenotype in primary cutaneous melanoma and mucosal melanoma and their clinical significance and prognostic value: a study of 89 consecutive cases
    Ren, Yu
    Lv, Qing
    Yue, Wuheng
    Liu, Baorui
    Zou, Zhengyun
    MELANOMA RESEARCH, 2020, 30 (01) : 85 - 101
  • [40] Tumor responses and early onset cytokine release syndrome in synovial sarcoma patients treated with a novel affinity-enhanced NY-ESO-1-targeting TCR-redirected T cell transfer.
    Ishihara, Mikiya
    Kitano, Shigehisa
    Hattori, Hiroyoshi
    Miyahara, Yoshihiro
    Kato, Hidefumi
    Mishima, Hideyuki
    Yamamoto, Noboru
    Funakoshi, Takeru
    Kojima, Takashi
    Sasada, Tetsuro
    Sato, Eiichi
    Okamoto, Sachiko
    Tomura, Daisuke
    Chono, Hideto
    Nukaya, Ikuei
    Mineno, Junichi
    Ikeda, Hiroaki
    Watanabe, Takashi
    Kageyama, Shinichi
    Shiku, Hiroshi
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)