A dendritic cell targeting NY-ESO-1 vaccine significantly augments early and durable immune responses in melanoma patients pretreated with human Flt-3 Ligand

被引：0

作者：

Bhardwaj, Nina ^{[1
]}

Friedlander, Philip ^{[2
]}

Pavlick, Anna ^{[3
]}

Ernstoff, Marc ^{[4
]}

Gastman, Brian ^{[5
]}

Hanks, Brent ^{[6
]}

Albertini, Mark ^{[7
]}

Luke, Jason ^{[8
]}

Yellin, Michael ^{[9
]}

Keler, Tibor ^{[9
]}

Davis, Thomas ^{[9
]}

Vitale, Laura ^{[9
]}

Blazquez, Ana ^{[10
]}

Morishima, Chihiro ^{[11
]}

Danaher, Patrick ^{[12
]}

Warren, Sarah ^{[12
]}

Salim, Bob ^{[13
]}

Hess, Bruce ^{[11
]}

D'Amico, Leonard ^{[11
]}

Lundgren, Lisa ^{[14
]}

Disis, Nora ^{[11
]}

Cheever, Martin ^{[14
]}

Fling, Steven ^{[14
]}

机构：

[1] Icahn Sch Med Mt Sinai, New York, NY 10029 USA

[2] Mt Sinai Beth Israel, New York, NY USA

[3] NYU Lagone Med Ctr, New York, NY USA

[4] Roswell Pk Canc Inst, Buffalo, NY USA

[5] Cleveland Clin, Cleveland, OH 44106 USA

[6] Duke, Durham, NC USA

[7] Univ Wisconsin, Madison, WI USA

[8] Univ Chicago Med, Chicago, IL USA

[9] Celldex Therapeut, Needham, MA USA

[10] Mt Sinai, New York, NY USA

[11] Univ Washington, Seattle, WA 98195 USA

[12] Nanostring Technol, Seattle, WA USA

[13] Axio Res, Seattle, WA USA

[14] Fred Hutchinson Canc Res Ctr, 1124 Columbia St, Seattle, WA 98104 USA

来源：

JOURNAL FOR IMMUNOTHERAPY OF CANCER | 2017年 / 5卷

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页数：2

共 43 条

[1] Flt3 ligand augments immune responses to anti-DEC-205-NY-ESO-1 vaccine through expansion of dendritic cell subsets
Nina Bhardwaj
Philip A. Friedlander
Anna C. Pavlick
Marc S. Ernstoff
Brian R. Gastman
Brent A. Hanks
Brendan D. Curti
Mark R. Albertini
Jason J. Luke
Ana B. Blazquez
Sreekumar Balan
Davide Bedognetti
Joseph M. Beechem
Andrea S. Crocker
Leonard D’Amico
Patrick Danaher
Thomas A. Davis
Thomas Hawthorne
Bruce W. Hess
Tibor Keler
Lisa Lundgren
Chihiro Morishima
Nirasha Ramchurren
Darawan Rinchai
Andres M. Salazar
Bob A. Salim
Elad Sharon
Laura A. Vitale
Ena Wang
Sarah Warren
Michael J. Yellin
Mary L. Disis
Martin A. Cheever
Steven P. Fling
Nature Cancer, 2020, 1 : 1204 - 1217
[2] Flt3 ligand augments immune responses to anti-DEC-205-NY-ESO-1 vaccine through expansion of dendritic cell subsets
Bhardwaj, Nina
Friedlander, Philip A.
Pavlick, Anna C.
Ernstoff, Marc S.
Gastman, Brian R.
Hanks, Brent A.
Curti, Brendan D.
Albertini, Mark R.
Luke, Jason J.
Blazquez, Ana B.
Balan, Sreekumar
Bedognetti, Davide
Beechem, Joseph M.
Crocker, Andrea S.
D'Amico, Leonard
Danaher, Patrick
Davis, Thomas A.
Hawthorne, Thomas
Hess, Bruce W.
Keler, Tibor
Lundgren, Lisa
Morishima, Chihiro
Ramchurren, Nirasha
Rinchai, Darawan
Salazar, Andres M.
Salim, Bob A.
Sharon, Elad
Vitale, Laura A.
Wang, Ena
Warren, Sarah
Yellin, Michael J.
Disis, Mary L.
Cheever, Martin A.
Fling, Steven P.
NATURE CANCER, 2020, 1 (12) : 1204 - +
[3] A Phase II Randomized Study of CDX-1401, a Dendritic Cell Targeting NY-ESO-1 Vaccine, in Patients with Malignant Melanoma Pre-Treated with Recombinant CDX-301, a Recombinant Human Flt3 Ligand.
Bhardwaj, Nina
Pavlick, Anna C.
Ernstoff, Marc S.
Hanks, Brent Allen
Albertini, Mark R.
Luke, Jason John
Yellin, Michael Jay
Keler, Tibor
Davis, Thomas A.
Crocker, Andrea
Vitale, Laura
Morishima, Chihiro
Friedlander, Philip Adam
Cheever, Martin A.
Fling, Steven
JOURNAL OF CLINICAL ONCOLOGY, 2016, 34 (15)
[4] Evaluation of cyclophosphamide as an immune enhancer for the NY-ESO-1/ISCOMATRIX vaccine in patients with metastatic melanoma.
Klein, Oliver
Davis, Ian D.
McArthur, Grant A.
Haydon, Andrew Mark
Parente, Phillip
Dimopoulos, Nektaria
Jackson, Heather
Maraskovsky, Eugene
Hopkins, Wendie
Stan, Rodica
Chen, Weisan
Cebon, Jonathan S.
JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (15)
[5] Induction of Antigen-Specific Immunity with a Vaccine Targeting NY-ESO-1 to the Dendritic Cell Receptor DEC-205
Dhodapkar, Madhav V.
Sznol, Mario
Zhao, Biwei
Wang, Ding
Carvajal, Richard D.
Keohan, Mary L.
Chuang, Ellen
Sanborn, Rachel E.
Lutzky, Jose
Powderly, John
Kluger, Harriet
Tejwani, Sheela
Green, Jennifer
Ramakrishna, Venky
Crocker, Andrea
Vitale, Laura
Yellin, Michael
Davis, Thomas
Keler, Tibor
SCIENCE TRANSLATIONAL MEDICINE, 2014, 6 (232)
[6] Specific cellular immune responses against NY-ESO-1 are associated with favorable survival of stage IV melanoma patients
Weide, B.
Zelba, H.
Derhovanessian, E.
Pflugfelder, A.
Schadendorf, D.
de Vries, J.
Maio, M.
Garbe, C.
Pawelec, G.
JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT, 2011, 9 (09): : 781 - 782
[7] Regulatory T-Cell - Mediated Attenuation of T-Cell Responses to the NY-ESO-1 ISCOMATRIX Vaccine in Patients with Advanced Malignant Melanoma
Nicholaou, Theo
Ebert, Lisa M.
Davis, Ian D.
McArthur, Grant A.
Jackson, Heather
Dimopoulos, Nektaria
Tan, Bee
Maraskovsky, Eugene
Miloradovic, Lena
Hopkins, Wendie
Pan, Linda
Venhaus, Ralph
Hoffman, Eric W.
Chen, Weisan
Cebon, Jonathan
CLINICAL CANCER RESEARCH, 2009, 15 (06) : 2166 - 2173
[8] Human Flt-3 ligand-mobilized dendritic cells, require additional activation to drive effective immune responses
Diener, Kerrilyn R.
Moldenhauer, Lachlan M.
Lyons, A. Bruce
Brown, Michael P.
Hayball, John D.
EXPERIMENTAL HEMATOLOGY, 2008, 36 (01) : 51 - 60
[9] Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients
Kageyama, Shinichi
Wada, Hisashi
Muro, Kei
Niwa, Yasumasa
Ueda, Shugo
Miyata, Hiroshi
Takiguchi, Shuji
Sugino, Sahoko H.
Miyahara, Yoshihiro
Ikeda, Hiroaki
Imai, Naoko
Sato, Eiichi
Yamada, Tomomi
Osako, Masaharu
Ohnishi, Mami
Harada, Naozumi
Hishida, Tadashi
Doki, Yuichiro
Shiku, Hiroshi
JOURNAL OF TRANSLATIONAL MEDICINE, 2013, 11
[10] Dose-dependent effects of NY-ESO-1 protein vaccine complexed with cholesteryl pullulan (CHP-NY-ESO-1) on immune responses and survival benefits of esophageal cancer patients
Shinichi Kageyama
Hisashi Wada
Kei Muro
Yasumasa Niwa
Shugo Ueda
Hiroshi Miyata
Shuji Takiguchi
Sahoko H Sugino
Yoshihiro Miyahara
Hiroaki Ikeda
Naoko Imai
Eiichi Sato
Tomomi Yamada
Masaharu Osako
Mami Ohnishi
Naozumi Harada
Tadashi Hishida
Yuichiro Doki
Hiroshi Shiku
Journal of Translational Medicine, 11

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