Genetic Determinants for Cadmium and Arsenic Resistance among Listeria monocytogenes Serotype 4b Isolates from Sporadic Human Listeriosis Patients

被引:38
|
作者
Lee, Sangmi [1 ]
Rakic-Martinez, M. [1 ]
Graves, L. M. [2 ]
Ward, T. J. [3 ]
Siletzky, R. M. [1 ]
Kathariou, S. [1 ]
机构
[1] N Carolina State Univ, Dept Food Bioproc & Nutr Sci, Raleigh, NC 27695 USA
[2] Ctr Dis Control & Prevent, Enter Dis Lab Branch, Natl Ctr Emerging & Zoonot Infect Dis, Atlanta, GA USA
[3] ARS, Bacterial Foodborne Pathogens & Mycol Res Unit, USDA, Peoria, IL USA
关键词
BENZALKONIUM CHLORIDE RESISTANCE; PLASMID-BORNE CADMIUM; HEAVY-METAL; FOOD SAFETY; STRAINS; SEQUENCE; VIRULENCE; LINEAGE; ILLNESS; MARKERS;
D O I
10.1128/AEM.03551-12
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
In Listeria monocytogenes serotype 4b isolates from sporadic listeriosis, heavy metal resistance was primarily encountered in certain clonal groups (ECI, ECII, and ECIa). All arsenic-resistant isolates harbored the arsenic resistance cassette previously identified in pLI100; ECIa harbored additional arsenic resistance genes and a novel cadmium resistance determinant in a conserved chromosomal locus.
引用
收藏
页码:2471 / 2476
页数:6
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