The mucosal immune system of the respiratory tract

被引：89
|
作者：
Sato, Shintaro [1 ]
Kiyono, Hiroshi [1 ]
机构：
[1] Univ Tokyo, Inst Med Sci, Dept Microbiol & Immunol, Div Mucosal Immunol,Minato Ku, Tokyo 1088639, Japan
来源：
CURRENT OPINION IN VIROLOGY | 2012年 / 2卷 / 03期
基金：
日本科学技术振兴机构;
关键词：
NATURAL-KILLER-CELLS; LYMPHOID-TISSUE BALT; INFLUENZA INFECTION; MOLECULAR-BASIS; PEYERS-PATCHES; CUTTING EDGE; RIG-I; IGA; RECOGNITION; EXPRESSION;
D O I：
10.1016/j.coviro.2012.03.009
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Most viruses use host mucosal surfaces as their initial portals of infection. The respiratory tract has the body's second-largest mucosal surface area after the digestive tract. An understanding of the unique nature of the mucosal immune system of respiratory organs is therefore extremely important for the development of new-generation vaccines and novel methods of preventing and treating respiratory infectious diseases, including viral infections.
引用
收藏
页码：225 / 232
页数：8
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