Electrochemically directed biofunctionalization of a lossy-mode resonance optical fiber sensor

被引:13
|
作者
Janik, Monika [1 ,2 ]
Niedzialkowski, Pawel [1 ,3 ]
Lechowicz, Katarzyna [1 ]
Koba, Marcin [1 ,4 ]
Sezemsk, Petr [5 ]
Stranak, Vitezslav [5 ]
Ossowski, Tadeusz [1 ]
Smietana, Mateusz J. [1 ]
机构
[1] Warsaw Univ Technol, Inst Microelect & Optoelect, Koszykowa 75, PL-00662 Warsaw, Poland
[2] Gdansk Univ Technol, Fac Elect Telecommun & Informat, Dept Metrol & Optoelect, Narutowicza 11-12, PL-80233 Gdansk, Poland
[3] Univ Gdansk, Fac Chem, Dept Analyt Chem, Wita Stwosza 63, PL-80308 Gdansk, Poland
[4] Natl Inst Telecommun, Szachowa 1, PL-04894 Warsaw, Poland
[5] Univ South Bohemia, Fac Sci, Inst Phys & Biophys, Branisovska 1760, Ceske Budejovice 37005, Czech Republic
来源
OPTICS EXPRESS | 2020年 / 28卷 / 11期
关键词
ELECTRON-TRANSFER KINETICS; AVIDIN-BIOTIN INTERACTION; NANOPARTICLES; SURFACES;
D O I
10.1364/OE.390780
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
In this work, we present a direct electrochemical biofunctionalization of an indium-tin-oxide-coated lossy-mode resonance optical fiber sensor. The functionalization using a biotin derivative was performed by cyclic voltammetry in a 10 mM biotin hydrazide solution. All stages of the experiment were simultaneously verified with optical and electrochemical techniques. Performed measurements indicate the presence of a poly-biotin layer on the sensor's surface. Furthermore, dual-domain detection of 0.01 and 0.1 mg/mL of avidin confirms the sensor's viability for label-free detection. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement
引用
收藏
页码:15934 / 15942
页数:9
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