Electrochemically directed biofunctionalization of a lossy-mode resonance optical fiber sensor

被引：13

作者：

Janik, Monika ^{[1
,2
]}

Niedzialkowski, Pawel ^{[1
,3
]}

Lechowicz, Katarzyna ^{[1
]}

Koba, Marcin ^{[1
,4
]}

Sezemsk, Petr ^{[5
]}

Stranak, Vitezslav ^{[5
]}

Ossowski, Tadeusz ^{[1
]}

Smietana, Mateusz J. ^{[1
]}

机构：

[1] Warsaw Univ Technol, Inst Microelect & Optoelect, Koszykowa 75, PL-00662 Warsaw, Poland

[2] Gdansk Univ Technol, Fac Elect Telecommun & Informat, Dept Metrol & Optoelect, Narutowicza 11-12, PL-80233 Gdansk, Poland

[3] Univ Gdansk, Fac Chem, Dept Analyt Chem, Wita Stwosza 63, PL-80308 Gdansk, Poland

[4] Natl Inst Telecommun, Szachowa 1, PL-04894 Warsaw, Poland

[5] Univ South Bohemia, Fac Sci, Inst Phys & Biophys, Branisovska 1760, Ceske Budejovice 37005, Czech Republic

来源：

OPTICS EXPRESS | 2020年 / 28卷 / 11期

关键词：

ELECTRON-TRANSFER KINETICS; AVIDIN-BIOTIN INTERACTION; NANOPARTICLES; SURFACES;

D O I：

10.1364/OE.390780

中图分类号：

O43 [光学];

学科分类号：

070207 ; 0803 ;

摘要：

In this work, we present a direct electrochemical biofunctionalization of an indium-tin-oxide-coated lossy-mode resonance optical fiber sensor. The functionalization using a biotin derivative was performed by cyclic voltammetry in a 10 mM biotin hydrazide solution. All stages of the experiment were simultaneously verified with optical and electrochemical techniques. Performed measurements indicate the presence of a poly-biotin layer on the sensor's surface. Furthermore, dual-domain detection of 0.01 and 0.1 mg/mL of avidin confirms the sensor's viability for label-free detection. (C) 2020 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

引用

页码：15934 / 15942

页数：9

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