Block of Herg by Trapped Drugs Shows a Different Dependency on Extracellular Potassium Compared to Block of Herg by Drugs That are Not Trapped

被引：0
|
作者：
Dodyk, Katrina [1 ]
Chu, Elaine [1 ]
Gjerde, Christine [1 ]
Miller, Alan [1 ]
机构：
[1] Touro Univ Calif, Vallejo, CA USA
来源：
BIOPHYSICAL JOURNAL | 2010年 / 98卷 / 03期
关键词：
D O I：
10.1016/j.bpj.2009.12.655
中图分类号：
Q6 [生物物理学];
学科分类号：
071011 ;
摘要：
引用
收藏
页码：120A / 120A
页数：1
相关论文
共 50 条
  • [41] Block of HERG potassium channels expressed in HEK-293 cells by the general anaesthetic, propofol
    Peri, R
    Brown, BS
    BIOPHYSICAL JOURNAL, 2002, 82 (01) : 582A - 582A
  • [42] Altering extracellular potassium concentration does not modulate drug block of human ether-a-go-go-related gene (hERG) channels
    Limberis, James T.
    Su, Zhi
    Cox, Bryan F.
    Gintant, Gary A.
    Martin, Ruth L.
    CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY, 2006, 33 (11) : 1059 - 1065
  • [43] Modeling hERG and its interactions with drugs: Recent advances in light of current potassium channel simulations
    Recanatini, Maurizio
    Cavalli, Andrea
    Masetti, Matteo
    CHEMMEDCHEM, 2008, 3 (04) : 523 - 535
  • [44] State-dependent block of HERG potassium channels by R-roscovitine: implications for cancer therapy
    Ganapathi, Sindura B.
    Kester, Mark
    Elmslie, Keith S.
    AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY, 2009, 296 (04): : C701 - C710
  • [45] Torsadogenic cardiotoxicity of antipsychotic drugs: a structural feature, potentially involved in the interaction with cardiac HERG potassium channels
    Testai, L
    Bianucci, AM
    Massarelli, I
    Breschi, MC
    Martinotti, E
    Calderone, V
    CURRENT MEDICINAL CHEMISTRY, 2004, 11 (20) : 2691 - 2706
  • [46] Block effect of capsaicin on hERG potassium currents is enhanced by S6 mutation at Y652
    Xing, Junlian
    Ma, Jihua
    Zhang, Peihua
    Fan, Xinrong
    EUROPEAN JOURNAL OF PHARMACOLOGY, 2010, 630 (1-3) : 1 - 9
  • [47] The anti-malarial drug halofantrine and its metabolite N-desbutylhalofantrine block HERG potassium channels
    Mbai, M
    Rajamani, S
    January, CT
    CARDIOVASCULAR RESEARCH, 2002, 55 (04) : 799 - 805
  • [48] Dynamic Action Potential Clamp Investigation of Pro-Arrhythmic Risk of Drugs Binding to hERG Potassium Channels
    Mann, Stefan A.
    Vandenberg, Jamie I.
    BIOPHYSICAL JOURNAL, 2014, 106 (02) : 553A - 553A
  • [49] Non-cardiovascular drugs that inhibit hERG-encoded potassium channels and risk of sudden cardiac death
    van Noord, Charlotte
    Sturkenboom, Miriam C. J. M.
    Straus, Sabine M. J. M.
    Witteman, Jacqueline C. M.
    Stricker, Bruno H. Ch
    HEART, 2011, 97 (03) : 215 - 220
  • [50] Non-Cardiovascular Drugs that Inhibit hERG-Encoded Potassium Channels and Risk of Sudden Cardiac Death
    van Noord, Charlotte
    Sturkenboom, Miriam C. J. M.
    Straus, Sabine M. J. M.
    Witteman, Jacqueline C. M.
    Stricker, Bruno H. Ch.
    DRUG SAFETY, 2009, 32 (10) : 956 - 956
12345