Angiotensin-Converting Enzyme Inhibitors Induce Cough

被引：26
|
作者：
Yilmaz, Insu [1 ]
机构：
[1] Erciyes Univ, Sch Med, Div Immunol & Allergy, Dept Chest Dis, Kayseri, Turkey
来源：
TURKISH THORACIC JOURNAL | 2019年 / 20卷 / 01期
关键词：
Cough; angiotensin converting enzyme inhibitors; hypertension; ACE-INHIBITORS; BRONCHIAL HYPERREACTIVITY; DIAGNOSTIC EVALUATION; GENE POLYMORPHISM; ADVERSE-REACTIONS; KEY COMPONENTS; RECEPTOR GENE; CAPTOPRIL; HYPERTENSION; SENSITIVITY;
D O I：
10.5152/TurkThoracJ.2018.18014
中图分类号：
R56 [呼吸系及胸部疾病];
学科分类号：
摘要：
Angiotensin-converting enzyme inhibitors (ACE-I) are widely used in diseases, such as hypertension, congestive heart failure, and myocardial infarction. Although these drugs are well tolerated, one out of five patients discontinues ACE-I due to drug side effects, mainly chronic cough. However, the pathogenesis of ACE-I-induced cough remains controversial and requires further study. In this review, the mechanisms that are suggested in ACE-I-induced cough pathophysiology will be discussed in detail in light of the current literature.
引用
收藏
页码：36 / 42
页数：7
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