Hair cell afferent synapses

被引：58
|
作者：
Glowatzki, Elisabeth [1 ]
Grant, Lisa [1 ]
Fuchs, Paul [1 ]
机构：
[1] Johns Hopkins Sch Med, Dept Otolaryngol, Baltimore, MD 21205 USA
来源：
CURRENT OPINION IN NEUROBIOLOGY | 2008年 / 18卷 / 04期
关键词：
D O I：
10.1016/j.conb.2008.09.006
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
This review will cover advances in the study of hair cell afferent synaptic function occurring between 2005 and 2008. During this time, capacitance measurements of vesicular fusion have continued to be refined, optical methods have added insights regarding vesicle trafficking, and paired intracellular recordings have established the transfer function of the afferent synapse at high resolution. Further, genes have been identified with forms of deafness known as auditory neuropathy, and their role in afferent signaling explored in mouse models. With these advances, our view of the hair cell afferent synapse has continued to be refined, and surprising properties have been revealed that emphasize the unique role of this structure in neural function.
引用
收藏
页码：389 / 395
页数：7
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