Resistant Starch and Pullulan Reduce Postprandial Glucose, Insulin, and GLP-1, but Have No Effect on Satiety in Healthy Humans

被引：71
|
作者：
Klosterbuer, Abby S. [1 ]
Thomas, William [2 ]
Slavin, Joanne L. [1 ]
机构：
[1] Univ Minnesota, Dept Food Sci & Nutr, St Paul, MN 55508 USA
[2] Univ Minnesota, Sch Publ Hlth, Div Biostat, Minneapolis, MN 55455 USA
来源：
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 2012年 / 60卷 / 48期
关键词：
fiber; satiety; gut hormones; glucose; visual analog scale; DIETARY FIBER; FOOD-INTAKE; APPETITE SENSATIONS; PLASMA-GLUCOSE; SOLUBLE FIBER; ENERGY-INTAKE; GHRELIN; RESPONSES; WEIGHT; FAT;
D O I：
10.1021/jf303083r
中图分类号：
S [农业科学];
学科分类号：
09 ;
摘要：
The aim of this study was to determine the effects of three novel fibers on satiety and serum parameters. In a randomized, double-blind, crossover design, fasted subjects (n = 20) consumed a low-fiber control breakfast or one of four breakfasts containing 25 g of fiber from soluble corn fiber (SCF) or resistant starch (RS), alone or in combination with pullulan (SCF+P and RS+P). Visual analog scales assessed appetite, and blood samples were collected to measure glucose, insulin, ghrelin, and glucagon-like peptide-1 (GLP-1). The fiber treatments did not influence satiety or energy intake compared to control. RS+P significantly reduced glucose, insulin, and GLP-1, but neither SCF treatment differed from control. To conclude, these fibers have little impact on satiety when provided as a mixed meal matched for calories and macronutrients. Additional research regarding the physiological effects of these novel fibers is needed to guide their use as functional ingredients in food products.
引用
收藏
页码：11928 / 11934
页数：7
相关论文
共 50 条
  • [31] GLP-1 and Insulin Recruit Muscle Microvasculature and Dilate Conduit Artery Individually But Not Additively in Healthy Humans
    Tan, Alvin W. K.
    Subaran, Sharmila C.
    Sauder, Matthew A.
    Chai, Weidong
    Jahn, Linda A.
    Fowler, Dale E.
    Patrie, James T.
    Aylor, Kevin W.
    Basu, Ananda
    Liu, Zhenqi
    JOURNAL OF THE ENDOCRINE SOCIETY, 2018, 2 (02): : 190 - 206
  • [32] Effects of GLP-1 on regularity, frequency, amplitude, and mass of coordinate pulsatile insulin secretion in healthy humans
    Porksen, N
    Grofte, T
    Nyholm, B
    Veldhuis, JD
    Holst, JJ
    Schmitz, O
    Butler, PC
    DIABETOLOGIA, 1997, 40 : 493 - 493
  • [33] Exogenously imposed postprandial-like increases in systemic glucose and GLP-1 do not produce an incretin effect, suggesting a neural mechanism of GLP-1 action
    Ionut, V
    Liberty, IF
    Hucking, K
    Lottati, M
    Stefanovski, D
    Bergman, RN
    DIABETES, 2005, 54 : A362 - A362
  • [34] Exogenously imposed postprandial-like rises in systemic glucose and GLP-1 do not produce an incretin effect, suggesting an indirect mechanism of GLP-1 action
    Ionut, Viorica
    Liberty, Idit F.
    Hucking, Katrin
    Lottati, Maya
    Stefanovski, Darko
    Zheng, Dan
    Bergman, Richard N.
    AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2006, 291 (04): : E779 - E785
  • [35] Effect of endogenous GLP-1 on insulin secretion during oral glucose tolerance tests
    Salehi, Marzieh
    Vahl, Torsten
    D'Alessio, David A.
    DIABETES, 2006, 55 : A324 - A324
  • [36] Resistant Starch Combined with Whey Protein Increases Postprandial Metabolism and Lowers Glucose and Insulin Responses in Healthy Adult Men
    Mohr, Alex E.
    Minicucci, Olivia
    Long, Dale, Jr.
    Miller, Vincent J.
    Keller, Allison
    Sheridan, Caitlin
    O'brien, Gabriel
    Ward, Emery
    Schuler, Brad
    Connelly, Scott
    Holst, Jens J.
    Astrup, Arne
    He, Feng
    Gentile, Christopher L.
    Arciero, Paul J.
    FOODS, 2021, 10 (03)
  • [37] Effect of Single Oral Coingestion of GABA and Malic Acid on Postprandial GLP-1, Glucose, and Insulin Responses in Healthy Volunteers: A Randomized, Double-Blind, Placebo-Controlled, Crossover Study
    Noguchi, Hiroki
    Ikenaga, Takeshi
    Ueno, Shota
    Kohashi, Chieko
    Matsumura, Yasuhiro
    Kakumoto, Yusuke
    Kohda, Noriyuki
    Hara, Hiroshi
    Hira, Tohru
    MOLECULAR NUTRITION & FOOD RESEARCH, 2024, 68 (07)
  • [38] Effect of variety and cooking method on resistant starch content of white rice and subsequent postprandial glucose response and appetite in humans
    Chiu, Yu-Ting
    Stewart, Maria L.
    ASIA PACIFIC JOURNAL OF CLINICAL NUTRITION, 2013, 22 (03) : 372 - 379
  • [39] Acarbose may not have a direct effect an GLP-1 induced insulin release in rat pancreas perfusion
    Satman, I
    Zeybek, U
    Gurol, AO
    Tutuncu, Y
    Okten, A
    Yilmaz, T
    DIABETES, 1999, 48 : A424 - A424
  • [40] The effect of α- or β-casein addition to waxy maize starch on postprandial levels of glucose, insulin, and incretin hormones in pigs as a model for humans
    Kett, Anthony P.
    Bruen, Christine M.
    O'Halloran, Fiona
    Chaurin, Valerie
    Lawlor, Peadar G.
    O'Mahony, James A.
    Giblin, Linda
    Fenelon, Mark A.
    FOOD & NUTRITION RESEARCH, 2012, 56
12345