Monosomy 22 in a mixed germ cell sex cord stromal tumor of the ovary

被引：0
|
作者：
Speleman, F
Dermaut, B
DePotter, CR
VanGele, M
VanRoy, N
DePaepe, A
Laureys, G
机构：
[1] STATE UNIV GHENT HOSP,DEPT PATHOL,B-9000 GHENT,BELGIUM
[2] STATE UNIV GHENT HOSP,DEPT PEDIAT HEMATOONCOL,B-9000 GHENT,BELGIUM
来源：
GENES CHROMOSOMES & CANCER | 1997年 / 19卷 / 03期
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
We report the cytogenetic findings in a case of mixed germ cell-sex cord-stromal tumor of the ovary in a 5-month-old girl. Monosomy 22 was observed as the sole karyotypic abnormality. This result was confirmed by comparative genomic hybridization, which revealed no additional chromosomal imbalances. This is the first observation of a chromosomal aberration in a mixed germ cell-sex cord-stromal tumor of the ovary. Monosomy 22 has been previously observed in granulosa cell tumors of the ovary. This could suggest a common pathogenetic pathway for both types of tumors. (C) 1997 Wiley-Liss, Inc.
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页码：192 / 194
页数：3
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