Evasion of Influenza A Viruses from Innate and Adaptive Immune Responses

被引：158
|
作者：
van de Sandt, Carolien E. [1 ]
Kreijtz, Joost H. C. M. [1 ]
Rimmelzwaan, Guus F. [1 ]
机构：
[1] ErasmusMC, Dept Virol, NL-3015 GE Rotterdam, Netherlands
来源：
VIRUSES-BASEL | 2012年 / 4卷 / 09期
关键词：
influenza; evasion; innate immunity; adaptive immunity; CYTOTOXIC-T-LYMPHOCYTE; RESPIRATORY SYNCYTIAL VIRUS; CROSS-PROTECTIVE IMMUNITY; CELL-MEDIATED PROTECTION; AMINO-ACID SUBSTITUTION; TUMOR-NECROSIS-FACTOR; NATURAL-KILLER-CELLS; TOLL-LIKE RECEPTORS; DOUBLE-STRANDED-RNA; PRE-MESSENGER-RNAS;
D O I：
10.3390/v4091438
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
The influenza A virus is one of the leading causes of respiratory tract infections in humans. Upon infection with an influenza A virus, both innate and adaptive immune responses are induced. Here we discuss various strategies used by influenza A viruses to evade innate immune responses and recognition by components of the humoral and cellular immune response, which consequently may result in reduced clearing of the virus and virus-infected cells. Finally, we discuss how the current knowledge about immune evasion can be used to improve influenza A vaccination strategies.
引用
收藏
页码：1438 / 1476
页数：39
相关论文
共 50 条
  • [41] Hiding the evidence: two strategies for innate immune evasion by hemorrhagic fever viruses
    Hastie, Kathryn M.
    Bale, Shridhar
    Kimberlin, Christopher R.
    Saphire, Erica Ollmann
    [J]. CURRENT OPINION IN VIROLOGY, 2012, 2 (02) : 151 - 156
  • [42] Duck innate immune responses to high and low pathogenicity H5 avian influenza viruses
    Fleming-Canepa, Ximena
    Aldridge, Jerry R., Jr.
    Canniff, Lauren
    Kobewka, Michelle
    Jax, Elinor
    Webster, Robert G.
    Magor, Katharine E.
    [J]. VETERINARY MICROBIOLOGY, 2019, 228 : 101 - 111
  • [43] Innate and adaptive immune responses towardY nanomedicines
    de Oliveira Viana, Iara Maira
    Roussel, Sabrina
    Defrene, Joan
    Lima, Eliana Martins
    Barabe, Frederic
    Bertrand, Nicolas
    [J]. ACTA PHARMACEUTICA SINICA B, 2021, 11 (04) : 852 - 870
  • [44] Innate and adaptive immune responses against coronavirus
    Hosseini, Arezoo
    Hashemi, Vida
    Shomali, Navid
    Asghari, Faezeh
    Gharibi, Tohid
    Akbari, Morteza
    Gholizadeh, Saber
    Jafari, Abbas
    [J]. BIOMEDICINE & PHARMACOTHERAPY, 2020, 132
  • [45] Polyphosphazenes stimulate innate and adaptive immune responses
    Mutwiri, GK
    Benjamin, P
    Nichani, A
    Yost, R
    Andrianov, A
    Roberts, B
    Babiuk, LA
    [J]. FASEB JOURNAL, 2005, 19 (04): : A896 - A896
  • [46] Innate and adaptive immune responses to cell death
    Rock, Kenneth L.
    Lai, Jiann-Jyh
    Kono, Hajime
    [J]. IMMUNOLOGICAL REVIEWS, 2011, 243 : 191 - 205
  • [47] Innate and Adaptive Immune Responses in HELLP Syndrome
    Stojanovska, Violeta
    Zenclussen, Ana Claudia
    [J]. FRONTIERS IN IMMUNOLOGY, 2020, 11
  • [48] The art of war: Innate and adaptive immune responses
    Dempsey, PW
    Vaidya, SA
    Cheng, G
    [J]. CELLULAR AND MOLECULAR LIFE SCIENCES, 2003, 60 (12) : 2604 - 2621
  • [49] Epithelium: At the interface of innate and adaptive immune responses
    Schleimer, Robert P.
    Kato, Atsushi
    Kern, Robert
    Kuperman, Douglas
    Avila, Pedro C.
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 120 (06) : 1279 - 1284
  • [50] Exploring the innate and adaptive immune responses in asthma
    Laffman-Johnson, Elise
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2012, 92 (02) : 141 - 141
12345